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CMC Forum

February 2010

February 2010, Vol.8 No.2

On the Cover

Our downstream theme is illustrated by the end of that stream in this photo of vials in a fill–finish operation. Stefan Catalin, www.istockphoto.com

BioProcess Special Report

The Time Has Come for Automation in Bioprocessing

Cheryl Scott, Lorna D. McLeod

BioProcess International, Vol. 8, No. 2, February 2010, pp. 16–25

BioProcess Technical

Minibodies and Multimodal Chromatography Methods

Pete Gagnon, Chia-Wei Cheung, Eric J. Lepin, Anna M. Wu, Mark A. Sherman, Andrew A. Raubitschek, Paul J. Yazaki

BioProcess International, Vol. 8, No. 2, February 2010, pp. 26–35

Is Bovine Albumin Too Complex to Be Just a Commodity?

Frank J. Mannuzza, Joseph G. Montalto

BioProcess International, Vol. 8, No. 2, February 2010, pp. 40–43

Using In-Line Disposable Pressure Sensors to Evaluate Depth Filter Performance

Lee R. Bink, James Furey

BioProcess International, Vol. 8, No. 2, February 2010, pp. 44–49

Focus On…

INFORMATION TECHNOLOGY

Biopharmaceutical Information Infrastructure 2.0

Jaspinder Hans, Anshuman Bansal

BioProcess International, Vol. 8, No. 2, February 2010, pp. 28–32

Bioprocess Technical

Microanalytical Techniques for Identifying Nonprotein Contaminants in Biologics

Mary Stellmack

BioProcess International, Vol. 8, No. 2, February 2010, pp. 36–39

Vendor Voice

Novel Affinity Ligands Provide for Highly Selective Primary Capture

Frank Detmers, Pim Hermans, Jin-An Jiao, Justin T. McCue

BioProcess International, Vol. 8, No. 2, February 2010, pp. 50–54

Global Marketplace

BioProcess International, Vol. 8, No. 2, February 2010, pp. 56–58

Global Meetingplace

IBC's 24th International Antibody Development and Production

BioProcess International, Vol. 8, No. 2, February 2010, pp. 60–60

Elucidation

Embracing Biotechnology

Jeff Joseph

BioProcess International, Vol. 8, No. 2, February 2010, p. 64

The Best of GE Healthcare: Tools for vaccine processes

In vaccine development and manufacturing, GE Healthcare provides a suite of scalable solutions from cell culture through purification to analysis, which offer flexibility and economy, improve purity and secure quality.

Microcarriers and disposable bioreactors for MDCK and Vero cell culture
Secure cell propagation with adherent cells at reduced cost and with increased flexibility

DNA removal from influenza virus culture
HTPD and DoE for development and optimization of a chromatography step for the removal of host cell derived genomic DNA

Editors' Blog

CRS for the Next Generation

BPI’s Senior Technical Editor’s at the CRS Annual Meeting in Portland, OR This Week (7/12/10–7/14/10)

Practical Considerations for DoE Implementation in Quality By Design

Contractor Responsibilities in Outsourced Pharmaceutical Quality Control Testing

Measuring Manufacturing Cost and Its Impact on Organizations

Single-Use Technology

Fluorescence-Activated Cell Sorting for CGMP Processing of Therapeutic Cells

The Roles of Bioactivity Assays in Lot Release and Stability Testing

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