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Literature: OneTouch FPA brochure
Applications: Aseptic processing
Features: Meissner Filtration Products literature features its One-Touch single-use fluid-path assemblies designed for secure fluid transfer in critical biopharmaceutical processing applications. The brochure illustrates a number of common FPA process configurations using Meissner's library of prequalified components. Assemblies can include capsule filters for applications requiring filtration of 10-mL to >10,000-L volumes. Gamma irradiation data are covered as well. These assemblies can be customized and include dynamic combinations of connectivity, tubing, and other components.
Contact Meissner Filtration Products
Single-Use SensorsProduct: TruFluor and TruTorr sensors
Applications: Single-use bioreactors
Features: Finesse single-use GMP-qualified sensors come with Thermo Scientific HyClone's single-use containers and bioreactors and are integrated into the Finesse turn-key bioreactor system for 25–2,000 L process volumes. TruFluor sensors optically measure pH and dissolved oxygen using real-time phase fluorimetry. The TruTorr system measures headspace pressure. These USP class VI compliant, precalibrated sensors automatically compensate for temperature.
Contact Finesse Solutions LLC
QC AutomationProducts: Dip and Read residual protein A detection kit and Sidekick offline biosensor immobilization station
Applications: Quality control assays on the Octet platform
Features: The protein A detection kit includes biosensors and reagents for quantitating protein A or its biosimilars in the presence of human IgG antibodies. With the same sensitivity as other methods, this assay requires less hands-on work and can be completed in half the time. The Sidekick station provides off-line, simultaneous, and uniform sample loading on all 96 biosensors in an Octet tray. It shakes samples, keeping the biosensors immobile, to decrease required incubation time and increase the sensitivity of sandwich assays.
Contact ForteBio Inc.
Mycoplasma DetectionProduct: MilliPROBE detection system
Applications: Mycoplasma detection
Features: The MilliPROBE system integrates Millipore sample preparation technologies with molecular diagnostics technologies developed by Gen-Probe, Inc. (licensed to Roka Bioscience). Mycoplasma bacteria are difficult to detect and eliminate and can have costly consequences for biopharmaceutical manufacturers. This newest assay in the MilliPROBE platform cuts mycoplasma detection time from 28–35 days to just four hours. Faster and more robust detection enables biopharmaceutical manufacturers to test more frequently and take corrective action earlier in production process, reducing financial risks and optimizing product yields.
Contact Millipore Corporation
Label-Free AnalysisProduct: SPRimager II platform label-free peptide arrays
Applications: Antibody analysis
Features: Peptides make attractive affinity probes because of their robustness and specificity. This format allows users to analyze crude samples, saving the time and expense of purification. The array format increases the number of samples per test while decreasing the quantities of material needed. Label-free analysis facilitates collection of real-time interaction data and valuable affinity information. These peptide arrays allow specific detection of antibody targets in serum and egg yolks.
Contact GWC Technologies
BiobankingProduct: Nautilus software
Service: Fisher BioServices
Applications: Biological sample maintenance, analysis, and retrieval
Features: Nautilus biospecimen tracking software is designed for specimen collection, tracking, and storage with data capture, location management, chain-of-custody, and handling assurance. Fisher BioServices offers comprehensive, turn-key biobanking/biorepository services including collection kits, transportation, processing, testing, storage, and data management — all with remote access. Fisher BioServices currently manages >170,000,000 biological specimens, cell lines, tissues blood products and environmental samples.
Contact Thermo Fisher Scientific, Inc.
Valve–ConnectorProduct: Part #80206
Applications: Disposable fluid paths
Features: Qosina's part #80206 is both a Y connector and a check valve featuring two 0.157-in. ID ports and a nonreturn valve on the female Luer lock sidearm. The housing is made of acrylonitrile butadiene styrene (ABS) plastic, and the compression-resistant silicone valve has a 43.5-psi cracking pressure. After fluid passes through, the valve returns to its normally closed position to prevent leaks. The company makes a wide range of disposable components — connectors, Luers, caps, clamps, adapters, stopcocks, valves, swabs, and spikes — at its ISO 9001:2000 and ISO 14001:2004 registered facility.
Contact Qosina
In vaccine development and manufacturing, GE Healthcare provides a suite of scalable solutions from cell culture through purification to analysis, which offer flexibility and economy, improve purity and secure quality.
Register to download these two NEW application notes:
Microcarriers and disposable bioreactors for MDCK and Vero cell culture
Secure cell propagation with adherent cells at reduced cost and with increased flexibility
DNA removal from influenza virus culture
HTPD and DoE for development and optimization of a chromatography step for the removal of host cell derived genomic DNA
BioProcess International Conference & Exhibition
Practical Considerations for DoE Implementation in Quality By Design
Contractor Responsibilities in Outsourced Pharmaceutical Quality Control Testing
Measuring Manufacturing Cost and Its Impact on Organizations
Fluorescence-Activated Cell Sorting for CGMP Processing of Therapeutic Cells
I'm Losing Cell Viability and Function at Different Points in My Process, and I Don't Know Why!