Friday, July 15, 2022 Daily Archives

Development of LentiVEX™ Packaging and Producer Cell Lines for Lentivirus Manufacture

This webcast features: Corinne Branciaroli, Group Leader, CLD Viral Manufacturing, OXGENE, a WuXi Advanced Therapies Company. Lentiviral (LV) vectors have significant potential for cell and gene therapy applications. CAR-T and TCR therapies are becoming established treatments for blood malignancies that don’t respond to current therapies, and novel research aims to also exploit the usage of LV vectors to target solid tumors. However, challenges remain within the LV vector manufacturing process, such as achieving scalability and robustness. These challenges contribute to…

Podcast: Cytiva cites COVID as driver for biopharma resilience

Emmanuel Ligner, CEO of self-described bioprocess “critical actor” Cytiva talks us through the changing biomanufacturing landscape and unveils his firm’s sustainability report in the latest BioProcess Insider Expression Platform podcast. In 2021, Cytiva launched a survey measuring industry’s confidence in the biopharma space. Focusing across five pillars – supply chain resilience, talent pool, the R&D ecosystem, manufacturing agility, and government policy and regulation – the Biopharma Resilience Index averaged an overall score of 6.6 out of 10 in 2021. Feedback from 2022’s…

BeiGene teams with InnoRNA to develop mRNA therapeutics

Beijing-headquartered BeiGene has formed a global strategic collaboration with InnoRNA to develop mRNA therapeutics. Shenzhen, China-headquartered InnoRNA uses its LNP (liquid nanoparticle) delivery technology and mRNA drug discovery program to discover novel mRNA candidates. The collaboration will see InnoRNA receive an upfront cash payment and will be eligible to receive milestones and royalties on sales. BeiGene will hold exclusive global development and commercialization rights for the collaboration’s mRNA-LNP therapies. InnoRNA will receive an additional upfront cash payment and milestones for…