Tuesday, September 20, 2022 Daily Archives

Celyad plant buy to accelerate growth for cell therapy CDMO Cellistic

by

Cellistic has agreed to buy Celyad Oncology’s capabilities in Mont-Saint-Guibert, Belgium to support its “rapidly growing” allogeneic iPSC manufacturing business. The deal will see Cellistic, the cell therapy contract development and manufacturing organization (CDMO) business of Ncardia BV, add the 11,000 square-foot facility located in Mont-Saint-Guibert – around 25km southwest of Brussels – from CAR-T developer Celyad. The site achieved GMP approval back in 2012 when Celyad was known as Cardio3 BioSciences. “The purchase price for the assets in the…

September 20, 2022

Gene therapy firms must consider patients when choosing rAAV production systems

by

Gene therapy developers need to carefully assess their choice of production platform to make sure it best fits likely demand, clinical timelines, and target patient population size. The advice comes from a study in Current Opinion in Biotechnology that looked at the pros and cons of currently available recombinant adeno-associated viral vector (rAAV) based production systems. The authors compared transient transfection (TT) – which is the most widely used rAAV manufacturing methods – with baculovirus expression vector (BEV) based systems…

September 20, 2022

Integrating PendoTECH Single Use Sensors for Industry 4.0

by

Industry 4.0 refers to the ongoing Fourth Industrial Revolution, which is currently transforming modern manufacturing and production practices through the use of smart technology and artificial intelligence. At a high level, Industry 4.0 has paved the way for the integration of manufacturing execution systems (MES) with enterprise resource plan (ERP) systems and supervisory control and data acquisition (SCADA) systems. Biopharmaceutical manufacturing is currently evolving with the progression of Industry 4.0. The integration of business and manufacturing systems in an intelligent,…

September 20, 2022