Thursday, October 6, 2022 Daily Archives

Robust and Scalable MAb Capture Facilitated by a Novel Convecdiff Membrane Structure

Alternative stationary phases are being developed to solve the shortcomings of bead chromatography processes, namely high diffusional resistance leading to long processing cycles (4–6 h). Targeted lifetimes of 75–150 bind and elute cycles, taking sometimes years to achieve and requiring cleaning and respective validation, storage, and column unpacking and repacking, elevate costs and introduce increasingly unacceptable bioburden risks. Chromatographic membranes, due to intrinsically high mass transfer rates, overcome these limitations, enabling residence times of seconds and full lifetime utilization (75–150…

Cytiva snaps up Cevec, boosting cell line and viral vector services

Cevec’s cell line development capabilities are a highly complementary addition to Cytiva’s bioprocessing portfolio, the firm says. The acquisition announced this morning sees Germany’s CEVEC and its 46 staff join bioprocess giant Cytiva for an undisclosed amount. The deal brings Cytiva a range of cell line development and viral vector manufacturing technologies, which Emmanuel Abate, president of Genomic Medicine at Cytiva, told BioProcess Insider will be “highly complementary” to the biomanufacturing tools and services offered by Cytiva and fellow Danaher…