Friday, October 7, 2022 Daily Archives

Building and demonstrating quality of mAb therapies from the ground up

The demand for monoclonal antibody (mAb) therapies is growing at an unprecedented rate likely due to their proven effectiveness in treating a wide range of illnesses. The recent pandemic is just one example of a situation where the potential of mAbs to reverse even the most severe disease was realized. This bodes well for mAb biosimilar manufacturers ready to bring many more products to market over the next decade. Public impact MAbs had a significant head start over novel technologies…

Ginkgo adds ‘circular’ RNA with Circularis buy

The addition of Circularis and its circular RNA technology will support growing demand for nucleic acid and advanced therapy services, says Ginkgo Bioworks. The deal, of which financials have not been disclosed, sees Ginkgo add Circularis’ promoter screening platform to its existing technology. According to Ginkgo, the platform enables ultra-high throughput screening of enhancers and promoters, and the firm sees circular RNA (circRNA) as a potential therapeutic modality. “Circularis is developing cutting edge circular RNA technology, and we expect a…

Series A funding to expand Wheeler Bio OK drug substance plant

Wheeler Bio has closed a Series A financing round, which it says will fund the expansion of its biologics drug substance facility in Oklahoma. Wheeler Bio, a contract development and manufacturing organization (CDMO) that uses its open-source platform, Portable CMC, to produce clinical batches of biologics and reagents says the financing round, led by Charles River Laboratories and various others, will expand its facility in the Ziggurat building in Oklahoma City. According to the CDMO, it is solving “the momentum drop”…

Moderna and China at impasse over mRNA COVID vaccine

Moderna is ‘eager’ to sell its mRNA vaccine in China but balks at the idea of transferring its technology or building a manufacturing facility in the country. The conditions being imposed by China are: Moderna must sign up with a China-based partner, transferring all its technology to the China company and allowing the China company to make the drug, or the company must build a China manufacturing facility, again with a China partner, which would not involve a technology transfer.…