Tuesday, December 13, 2022 Daily Archives

Simplify Residual DNA Quantitation in Viral Vector Production With qPCR and dPCR Tools

This webcast features: Jonas Buege, Senior Product Manager, Pharma Analytics, Thermo Fisher Scientific. Amongst the challenges for clinical grade viral vector production is the removal of residual DNA impurities from the final drug product. Unlike traditional biologics, undesirable copackaging of residual host cell DNA as well as plasmid DNA in the viral vector capsid can lead to elevated quantities. Regulatory scrutiny has increased due to safey concerns of not only larger amounts, but also potential for inclusion of longer residual…

China plant becomes latest in Thermo Fisher biomanufacturing network

The 860,000 square-foot facility in Hangzhou is Thermo Fisher’s first single-use manufacturing site in the Asia-Pacific region. The facility opened its doors last week offering customers clinical and commercial drug substance and drug product capabilities, housing Thermo Fisher’s HyPerforma single-use bioreactors and associated single-use equipment to a 2,000 L scale. The size of the capital expenditure has not been disclosed, and when asked the firm did not divulge how long it has taken for the facility to be built. The…