Wednesday, January 11, 2023 Daily Archives

Post-COVID bioprocess destocking but vendors optimistic for 2023

Vendors are feeling the economic impact of dwindling COVID-related bioproduction, but Thermo Fisher and Danaher remain unfazed, the firms said at JPM 2023. Many bioprocess vendors reported falling orders in the latter half of 2022 as biopharma reduced stock orders for vaccine and therapeutics following two years of unprecedented pandemic-related growth. This bioprocess destocking dynamic – described by some as a “swift normalization of demand” – was brought up at this week’s JP Morgan Healthcare Conference in San Francisco but…

Valo selects Exothera to develop oncolytic adenovirus

Valo Therapeutics Oy (ValoTx) has selected CDMO Exothera to develop a large-scale production process for clinical development of its oncolytic adenovirus, VALO-D102. ValoTx’s VALO-D102 is an oncolytic adenovirus, which the firm says is an essential component of its immuno-oncology platform PeptiCRAd (Peptide-coated Conditionally Replicating Adenovirus). “We take an oncolytic adenovirus (VALO-D102) and add immunogenic positively charged tumor peptides, which are adsorbed onto the negatively charged viral capsid to create PeptiCRAd,” a spokesperson for ValoTx told us. The platform works by…