Wednesday, March 1, 2023 Daily Archives

Beyond Standard Protein A Resin: Establishment of an Improved DSP Affinity Platform Step for Monoclonal Antibodies

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This webcast features: Manuel Matos, PhD, Field Application Scientist, Thermo Fisher Scientific and Marco Baldazzi, DSP Research Laboratory Technician, Menarini Biotech. While protein A affinity chromatography is the most commonly used method for monoclonal antibody (MAb) capture in clarified harvest coming from CHO cell cultivation, one significant challenge is the high cost of the media required when using these resins. Therefore, it’s crucial to evaluate alternative strategies that may reduce costs and increase productivity without affecting product quality attributes. In…

March 1, 2023

Facility buildout does not always begin with bricks, says Genentech

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The buildout of a facility ends with technology choices but starts with a purpose, vision, and people, says Roche’s Genentech.   Genentech — part of the Roche Group — broke ground on a $450 million expansion at its Oceanside, California site in February 2023; a site it says will work in unison with the recently completed $250 million Clinical Supply Center in South San Francisco (SSF).  But when thinking about building a facility, the question “where are we going with the…

March 1, 2023

eXmoor and Imophoron team to develop vax platform

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The collaboration aims to manufacture vaccines for clinical use at eXmoor’s Bristol, UK plant set to launch in Q3, 2023. Cell and gene therapy (CGT) firm eXmoor pharma has partnered with vaccine platform developer, Imophoron. The first step of the agreement will see eXmoor develop a scalable manufacturing platform for Imophoron’s vaccine technology. Under the terms of the agreement, the platform will initially be optimized for Imophoron’s Respiratory Syncytial Virus (RSV) targeted vaccine. After this, a technology transfer of the…

March 1, 2023