Friday, March 17, 2023 Daily Archives

Advantages of Mixed-Mode Chromatography in Host Cell Protein Removal

This webcast features: Thomas Valorose, Senior Product Manager, Astrea Bioseparations. Despite considerable advances in downstream purification for MAbs and other recombinant proteins from various expression systems, there remains a need for effective removal of process and product related impurities that could impact product safety, stability, and efficacy. Many workflows today utilize multiple steps to polish their product, including ion exchange and hydrophobic interactions. Utilizing mixed-mode purification techniques, Astrea Bioseparations delivers a solution that has several advantages over traditional workflows. By…

Samsung Biologics lays down $1.5bn for fifth plant

The facility will boast 180,000 liters of bioreactor capacity, bringing Samsung Biologics’s total capacity in Songdo, Korea to 784,000 liters. Contract development and manufacturing organization (CDMO) Samsung Biologics has confirmed it is pumping over KRW 1.98 trillion ($1.47 billion) into a fifth plant, with construction set to begin before June. According to a regulatory filing published this morning, the project aims “to enhance the company’s competitiveness in biologics market by expanding its manufacturing facility.” The firm expects operations to begin…