Tuesday, April 18, 2023 Daily Archives

Gamida wins FDA approval for off-the-shelf cell therapy

The US FDA has approved Gamida Cell’s Omisirge (omidubicel), an allogeneic cell therapy for patients with blood cancers who are set to undergo stem cell transplantation. Omisirge is a modified allogeneic cord blood-based cell therapy to quicken the recovery of neutrophils and reduce the risk of infection. It is intended for use in patients with blood cancers planned for umbilical cord blood transplantation following a myeloablative conditioning regimen, such as radiation or chemotherapy. The product, a single intravenous dose composed…

Merck to buy Prometheus for $10.8bn

Merck & Co. will add monoclonal antibody (mAb) candidate PRA023 to its pipeline by acquiring Prometheus Biosciences for $10.8 billion. Merck & Co. (known as MSD outside North America and Canada) will pay Prometheus, a Californian-based clinical-stage biotechnology firm that focuses on treatments for autoimmune diseases, $200 per share in cash to acquire the firm. Merck will gain Prometheus’ lead asset PRA023, which is a humanized mAb targeted to tumor necrosis factor (TNF)-like ligand 1A (TL1A) to treat immune diseases…