Tuesday, May 16, 2023 Daily Archives

Automated 32×32 Epitope Binning in a Single Assay

The selection of lead candidates in the development of therapeutic monoclonal antibodies (mAbs) is a critical decision. Designing a mAb that exhibits all the desired biological and pharmaceutical properties is challenging, and therefore, this process is primarily empirical. The classification of monoclonal antibodies (mAbs) based on their binding behavior can be a valuable tool for selecting promising candidates for further development. Such classification often involves grouping mAbs with similar epitope binding regions, which are known to share similar biological functions.…

NewBiologix launches with $50m to develop CGT platform

With $50 million in Series A funding, NewBiologix aims to tackle challenges associated with the production of recombinant adeno-associated virus (rAAV).   The recently launched Lausanne, Switzerland-based company, NewBiologix, focuses on rAAV vectors, which is a typical delivery vehicle used for gene therapies. The firm is developing a DNA-based platform for the advanced engineering of cell lines used to produce cell and gene therapies (CGT) and it will be applied to human (HEK-293) and mammalian (CHO) cell lines. “By engineering…

BPI Europe: Dutch industry board pushes country’s CGT prowess

Talent pool, logistics, and a collaborative ecosystem are three overarching reasons why your CGT firm should invest in the Netherlands, says Invest in Holland. The Netherlands Foreign Investment Agency (NFIA) works with the nationwide Invest in Holland network, which is a governmental organization. Marit Vink, project manager Life Sciences & Health at NFIA/Invest in Holland told delegates attending BPI Europe 2023, Amsterdam there is a “big focus” on cell and gene therapies (CGTs) in the country. The country is already…