Tuesday, June 6, 2023 Daily Archives

Use of DOE Screening to Select Resins for Monoclonal Antibody Purification

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Screening resins for monoclonal antibody (mAb) purification is complicated both by the number of resins available and the myriad variables that must be considered to optimize a purification workflow. Using a systematic screening approach, such as design of experiments (DOE), can simplify resin selection by enabling a comprehensive evaluation of multiple input factors and their impact on desired outputs. Read this whitepaper to learn more about: The limitations of a templated approach How to optimize chromatographic separations using DOE screening…

June 6, 2023

J&J on CGTs: ‘We are disease, not modality-centric’

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Johnson & Johnson (J&J) says it remains agnostic to modality type in favor of the end user despite its recent efforts in the cell and gene therapy (CGT) space. At last week’s Bernstein’s 39th Annual Strategic conference, Johnson & Johnson was asked about its strategy to evolve its pipeline, specifically with new technologies and modalities including CGTs, mRNA, gene editing, and gene silencing. “We are already in-house in cell therapy and in gene therapy,” stated CEO Joaquin Duato, referencing the…

June 6, 2023