Thursday, June 8, 2023 Daily Archives

Lonza Shapes Biotherapeutics Development Programs around Different CMC Paths

Getting to the clinic is a major milestone for biopharmaceutical companies. The drug development journey is long, expensive, resource straining, and risky due to high attrition rates. A large amount of data must be generated, collected, interpreted and correctly integrated for the First-in-Human (FIH)-enabling data package. When developing more complex formats such as bispecific antibodies, fusion and recombinant proteins, you are probably facing even tougher technical challenges which can lead to longer timelines. As a biopharmaceutical company, you also face…

Sartorius and Waters expand partnership with eye on continuous production

Sartorius will leverage its process scale multi-column chromatography with Waters’ process analytical technology to provide analytical data for downstream biomanufacturing. In October 2021, bioprocess vendor Sartorius struck a partnership with Waters to use its BioAccord Liquid Chromatography (LC)–MS System as a new bioprocess analyzer for its Ambr multi-parallel bioreactor systems in an effort to accelerate speed and increase accuracy in bioprocessing analysis. 18 months on and the partnership has expanded, with the new integrated mix aiming to deliver analytical data…

Voice of resin: Purolite talks US agarose expansion at BIO

Purolite says support from parent firm Ecolab helped drive plans for a facility in Pennsylvania aimed at bringing biologics resin direct to the US market. Bioprocess services and consumables firm Purolite will construct a plant in Landenberg, Pennsylvania, offering resin production facilities, cleanrooms, laboratories, and new office space, it was revealed this week. Speaking to BioProcess Insider at BIO in Boston, Hayley Crowe, SVP and general manager at Purolite, said the company’s first US facility was driven by Ecolab, which…