Liquid-formulation vaccines often require shipment and storage within a temperature-controlled supply chain (a cold chain) between manufacture and administration. Since 2020, mRNA vaccines against SARS-CoV-2 have received considerable attention for their extreme cold-chain specifications. For instance, Pfizer–BioNTech’s Comirnaty bivalent booster for adults and adolescents must be stored in specialized freezers set between –90 ï›°C and –60 ï›°C for as long as 18 months (1). Usually, however, vaccines are shipped and stored in conditions between 2 ï›°C and 8 ï›°C (the…