2010

PAT-Based In-Line Buffer Dilution

    Technological advancement has taken protein expression titers from concentrations measured in mg/L to those measured in g/L over just a few years (1). Annual demand for antibodies has reached several metric tons, which has spurred production of >100 kg batches of protein at a time (2). As upstream yields continue to increase, downstream purification involving process solution preparation and delivery must increase in proportion to keep pace with demand. That has placed facility and instrumentation capacity constraints front…

Global Marketplace

Inline Sampling Product: STA-PURE fluid sampling Applications: PAT sampling Features: Gore’s sampling system can be directly connected to 25-mm Ingold ports. Previously, such sampling required the use of TC adapters and O rings that can leak or get stuck in vessel ports. The STA-PURE solution uses a high-purity, highly compressible platinum-cured silicone adapter integrated with a single valve device. A single-use silicone sleeve is attached and presterilized with the device. When the valve body is inserted into a vessel port,…

Biopharmaceutical Development and Production Week

IBC’s Biopharmaceutical Development and Production Week covers today’s critical issues from all angles to provide you with a deeper understanding of the forces affecting your company and driving the bioprocessing industry. Customize your learning and networking experience with access to 700+ bioprocessing professionals under one roof 103 presenters to share strategies and lessons learned 45 exclusive case studies five shared plenary sessions two exhibit halls with >60 supplier companies. Together, these five conferences deliver the latest technical and scientific approaches…