Korean drugmaker Celltrion has paid KRW 1 billion ($700,000) to access Pinot Bio’s antibody-drug conjugate (ADC) linker-payload technology. The PINOT-ADC platform, comprising of an independent drug and linker technology, overcomes the resistance limitations of existing ADC drugs, according to developer Pinot Bio. As such, fellow Korean firm Celltrion has tapped up the technology, forging a deal for up to 15 ADC candidates targeting solid tumor cancers using the platform. According to the Korea Biomedical Review, on top of the KRW…

Deal-Making
Samsung Biologics wins $296m 10-year GSK contract
GSK has doubled down on its partnership with Samsung Biologics, inking a deal valued at 26.8% of the Korean CDMO’s 2021 revenues. Details of the contract, released in a regulatory filing today, show that Pharma Giant GlaxoSmithKline has entered into a contract with Samsung Biologics worth KRW 420,667,219,640 ($296 million) beginning October 11 2022 and ending December 31 2030. The deal represents 26.8% of the contract development and manufacturing organization’s (CDMO’s) full year 2021 revenues of KRW 1,568,006,928,039. GSK already…
Lilly $487m+ Akouos buy to add hearing loss gene therapy programs
Nearly two years after buying Prevail Therapeutics, Eli Lilly is doubling down on its gene therapy presence through the acquisition of Akouos. Eli Lilly will pay $12.50 a share for Boston, Massachusetts-based Akouos, equating to around $487 million. The Big Pharma firm could pay a further one contingent value right (CVR) of up to $3 per share, adding another $123 million to the deal. Akouos is developing gene therapies to address hearing loss conditions, with its lead candidate AK-OTOF set…
Inceptor and Avectas team to improve CAR-T manufacturing
The collaboration between Inceptor Bio and Avectas will aim to improve the development and production of CAR-T cell therapies for the treatment of solid tumors. Financial details and length of the partnership remain under wraps. However, under the terms of the agreement, Inceptor will use Avectas’ Solupore technology as a substitute to electroporation for engineering T cells with the aim to produce an improved T cell product. In April 2021, Avectas received $8.7 million in funding to develop the cell…
BioNTech heads down under to build mRNA plant
BioNTech has entered into a partnership with the State of Victoria, Australia to construct a research and manufacturing center for mRNA-based products in Melbourne. According to the German biopharma company, the center will support “discovery to delivery” of messenger RNA (mRNA) vaccines and therapies. Additionally, as part of the collaboration, BioNTech will construct a BioNTainer facility for clinical scale manufacturing of mRNA-based products and candidates. A BioNTainer is a cleanroom built from six ISO sized containers and consisting of one…
Intravacc bags two intranasal vaccine deals in one week
A $14.6 million contract for its jointly developed gonorrhea vaccine and a partnership with CEPI to advance coronavirus vaccines make a busy week for Intravacc. Dutch firm, Intravacc, and microparticulate immune therapeutics firm Therapyxpartnered in August 2020 to develop NGoXIM, a prophylactic vaccine that treats gonorrhea. This week, the US National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has awarded the firms a contract with base and options that could potentially total…
Ginkgo adds ‘circular’ RNA with Circularis buy
The addition of Circularis and its circular RNA technology will support growing demand for nucleic acid and advanced therapy services, says Ginkgo Bioworks. The deal, of which financials have not been disclosed, sees Ginkgo add Circularis’ promoter screening platform to its existing technology. According to Ginkgo, the platform enables ultra-high throughput screening of enhancers and promoters, and the firm sees circular RNA (circRNA) as a potential therapeutic modality. “Circularis is developing cutting edge circular RNA technology, and we expect a…
Cytiva snaps up Cevec, boosting cell line and viral vector services
Cevec’s cell line development capabilities are a highly complementary addition to Cytiva’s bioprocessing portfolio, the firm says. The acquisition announced this morning sees Germany’s CEVEC and its 46 staff join bioprocess giant Cytiva for an undisclosed amount. The deal brings Cytiva a range of cell line development and viral vector manufacturing technologies, which Emmanuel Abate, president of Genomic Medicine at Cytiva, told BioProcess Insider will be “highly complementary” to the biomanufacturing tools and services offered by Cytiva and fellow Danaher…
Boehringer Ingelheim rolls out VR training at fill-finish facilities
Boehringer Ingelheim has deployed Virtuosi, a virtual training (VR) educational platform, across three of its aseptic manufacturing sites. Virtuosi, developed by Quality Executive Partners (QxP), claims to be the “world’s first” and singular multi-language immersive training platform training platform for the pharmaceutical manufacturing operators in aseptic processing, cell and gene therapy processing, and microbiology. The VR training platform will be deployed at Boehringer Ingelheim’s Biberach and Ingelheim sites in Germany, as well as a plant in Lyon, France. According to…
Rocket bolsters AAV pipeline with Renovacor buy
Rocket Pharmaceuticals will gain Renovacor’s program REN-001, an AAV-based gene therapy targeting BAG3-associated dilated cardiomyopathy (DCM) through the acquisition. Under the terms of the deal, Rocket, a firm focused on genetic therapies for rare childhood disorders, has acquired Renovacor, a company aiming to deliver precision therapies for individuals battling genetically-driven cardiovascular and mechanistically-related diseases. Rocket claims that the acquisition strengthens its adeno associated virus (AAV) based cardiac gene therapy leadership and scales the firm’s clinical assets for the treatment of…