This interview features: Jean Luo, Vice President and General Manager, Purification and Pharma Analytics, Thermo Fisher Scientific Jean Luo shared some of Thermo Fisher’s innovative new purification and PCR products at the BioProcess International West 2023 conference. She also discussed some efforts Thermo Fisher has taken to reduce lead times for supplies, as well as help customers avoid regulatory delays.
This interview features: Sebastian Giehring, CEO, PAIA. PAIA is presenting the world´s first assay for assessing mispairing of complex biotherapeutics based on charge differences. Mispairing is a huge challenge in the assembly of bispecific antibodies. It refers to the situation where chains from different monoclonal antibodies incorrectly pair with each other, producing process related impurities that have to be monotore during the bioprocess development. PAIA are showing data from one of the first bispecific biosimilars and illustrate the assay principle…
This presentation features: Milla Neffling, PhD, Market Segment Manager, 908 Devices. Faster development cycles, intensified processes, and automation of process control are key-initiatives in biotherapeutics manufacturing. However, offline analytics requiring manual intervention are commonly used to monitor critical and time-sensitive process parameters. We describe a new automated approach for optimal growth and production, leveraging sensitive, online (sample-free) monitoring of glucose and lactate with automated feed control, and its impact on growth/viability, lower metabolite, and improved PQA. Fill out the…
This interview features: William Barrett, PhD, Product Specialist, WL Gore & Associates. William Barrett, PhD is a product specialist with WL Gore & Associates. He has over 20 years combined experience in biotechnology, chromatography, and the medical device industries. Most recently at WL Gore, Bill’s focused on affinity purification chromatography. Previously, Bill worked at Agilent on affinity depletion devices used in biomarker discovery and proteomics. He received a PhD in biochemistry from the University of Illinois and completed his fellowship…
This interview features: Amy Bennett, Manager of Virology Scientific Support, Charles River Laboratories. Amy joined Charles River in 2010 as technician within the Virology Department and is now manager of Virology Scientific Support. She currently oversees development within the department as well as technical transfers. Amy has worked on the development and implementation of safety assays for various gene therapy vectors including adenovirus, adeno-associated virus, and lentivirus. She has a master’s degree in biology from West Chester University.
This interview features: Raphael Gübeli, PhD, Head of Marketing, c-LEcta. Dr. Raphael Gübeli, Head of Marketing at the German enzyme manufacturer c-LEcta will discuss recent trends related to the manufacturing of cell and gene therapies and how DENARASE® and other GMP enzymes can play an important role.
This interview features: Claes Gustafsson, Co-Founder and CCO, ATUM. Launched only a few years ago, the Leap-In Transposase platform has rapidly become an industry standard technology for the generation of CHO cells for the manufacturing of antibodies and other biologics. This presentation will highlight achievements and case studies of the platform including high titer MAb manufacturing, rapid anti-COVID responses, and some novel, next generation, applications. Speaker Bio: As ATUM’s Co-Founder and CCO, Dr. Claes Gustafsson oversees most of the…
This interview features: Mark Schofield, PhD, Senior R&D Manager, Pall Biotech. Schofield was interviewed at BPI West 2023 by Informa Connect Life Sciences Producer, Anna Brown about his talk on process intensification of monoclonal antibodies. Description: Streamlined process intensification of MAb production can provide a reduction in cost and increase accessibility. Here, a multifaceted approach is taken to address the process intensification of a biosimilar. Design of Experiments (DoEs) spanning sequential unit operations focused on the interconnectivity of the process,…