Facilities & Capacity

BioNTech buys Novartis plant to bring mRNA to Singapore

BioNTech is set to acquire a Novartis small molecule plant molecule site in Singapore and will transform it into the country’s first mRNA manufacturing facility.   In May 2021, BioNTech said it was aiming to bring messenger RNA (mRNA) manufacturing to Asia by building a facility in Singapore. 18 months on and the firm has now entered into an agreement to acquire a GMP-certified manufacturing facility on the island-state from pharma giant Novartis. “Novartis announced today that it has entered…

Novartis cuts 275 jobs at its IL plant to consolidate Zolgensma production

Novartis is closing the doors to its gene therapy manufacturing plant in Libertyville, Illinois following a manufacturing site network evaluation. According to Novartis, the reshape of the company will mean that operations concerning the production of Zolgensma (onasemnogene abeparvovec), a one-time spinal muscular atrophy (SMA) gene therapy — approved in the US in May 2019 –  will be consolidated to its Durham, North Carolina facility. “Following a comprehensive manufacturing site network evaluation, Novartis has made the difficult decision to cease operations at…

Feeling the cold: Envirotainer expansion to surpass a billion doses annually

Envirotainer says it has invested heavily to expand capacity and surpass a billion doses per year to meet future demand for temperature-controlled shipping at its Stockholm, Sweden plant. Envirotainer, a cold chain solution provider for the shipment of pharmaceuticals, has not disclosed specifical financial details of the expansion but said it has “invested heavily” at its production site in Rosersberg, north of Stockholm to up capacity to meet future need for temperature-controlled shipping. The company says the decision to expand…

Charles River ups cell therapy production with Memphis expansion

Charles River Laboratories says it will expand its cell therapy facility in Memphis, Tennessee to enable clients to streamline and accelerate their programs. Contract development manufacturing organization (CDMO) Charles River will increase its existing 16 cleanrooms by adding nine processing suites at its Memphis plant. The company says that the facility expansion will support its cell therapy clients and help them to speed their programs to commercialization. According to the firm, the suites will include advanced cleanroom facility technology and…

GEA breaks ground on $20m+ site in Wisconsin

GEA has started construction of its repair, logistics, assembly, production, and training facility located in Janesville, Wisconsin. According to the firm, the 85,000 square-foot building – which is GEA’s first greenfield site in North America in 50 years – aims to bring the company closer to its Midwest customer base and service their industry needs. “The Janesville facility will bring us closer to our growing Midwest customer base and it will enable us to meet the growing demand for our…

ReiThera opens Italy viral vector production plant

ReiThera has expanded its large-scale viral vector manufacturing capabilities at its Castel Romano Technopole plant through receiving operational authorization from the Italian Medicines Agency. According to the contract development manufacturing organization (CDMO), the recently opened 1,500 square meter facility located close to Rome will have production scales of up to 3,000 L and produce viral vectors for vaccines and gene therapies. “Thanks to the operational authorization of this expanded facility, the ReiThera team, which combines high-level scientific knowledge with extensive…

Vetter Pharma ups storage capacity with warehouse expansion

Vetter Pharma has completed its €20 million ($19 million) warehouse expansion, which it says will help meet customer supply demands. Contract development manufacturing organization (CDMO) Vetter says that the fully automated building located in Ravensburg, Germany optimizes the firm’s logistical infrastructure by providing storage space for materials it considers having high-stock turnover rates, such as packaging components. The firm claims that construction of the warehouse, which began in April 2021, will mean that “valuable capacity” is freed up in the…

Fill-finish roundup: News from INCOG, Recipharm, WuXi Bio

INCOG BioPharma completes installation of a filling line in Indiana, Recipharm invests in Lab+ filling technology in France, and WuXi Biologics expands its fill-finish capacity and capability in China. Welcome to our fill-finish roundup. First up is contract development manufacturing organization (CDMO) INCOG, which specializes in sterile injectables. The firm has completed the installation of its OPTIMA multi-use production filling line at its Fishers, Indiana plant. “The OPTIMA multi-use line serves as our highly customized, injectable therapy ‘bottling line’ at…

Lonza to expand US and EU CGT lab space

Lonza will expand its cell and gene therapy (CGT) development laboratories in the US at its Houston, Texas facility and in Europe at its plant in Geleen, The Netherlands. Swiss contract development manufacturing organization (CDMO) Lonza says the expansion in Houston will include viral vector-based process development and analytical development laboratories. In addition to its Houston expansion, the firm claims it will more than double its European process development laboratory space in Geleen, The Netherlands. The CDMO will add 4,500…

Landmark Bio opens advanced therapy manufacturing plant in MA

Academia-industry joint venture firm Landmark Bio says the recently opened Watertown, Massachusetts facility offers a one-stop-shop for manufacturing solutions. Harvard University, MIT, Fujifilm Diosynth Biotechnologies, Alexandria Real Estate Equities, and Cytiva – the founders of Landmark Bio – collectively invested $75 million to support construction staff and early client services for the 44,000 square-foot Watertown facility that will carry out development, manufacturing, and testing of cell and gene therapies in the area. Other collaborating institutions include Beth Israel Deaconess Medical…