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BioProcess International

Covering the whole development process for the global biotechnology industry

  • Upstream
    Processing
    Bioprocessing begins upstream, most often with culturing of animal or microbial cells in a range of vessel types (such as bags or stirred tanks) using different controlled feeding, aerating, and process strategies.
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    Processing
    Beginning with harvest of material from a bioreactor, downstream processing removes or reduces contaminants to acceptable levels through several steps that typically include centrifugation, filtration, and/or chromatographic technologies.
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    Drug products combine active pharmaceutical ingredients with excipients in a final formulation for delivery to patients in liquid or lyophilized (freeze-dried) packaged forms — with the latter requiring reconstitution in the clinical setting.
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    Many technologies are used to characterize biological products, manufacturing processes, and raw materials. The number of options and applications is growing every day — with quality by design (QbD) giving impetus to this expansion.
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    Even as it matures, the biopharmaceutical industry is still a highly entrepreneurial one. Partnerships of many kinds — from outsourcing to licensing agreements to consultancies — help companies navigate this increasingly global business environment.
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Issue Archive




Jan 2007 
Vol. 5, No. 1



Jan 2007 Supplement
Vol. 5, No. 1



Feb 2007 
Vol. 5, No. 2
 



Feb 2007 
Vol. 5, No. 2



Mar 2007 
Vol. 5, No. 3



Mar 2007 Supplement
Vol. 5, No. 1
 



Apr 2007 
Vol. 5, No. 4



May 2007 
Vol. 5, No. 5



May 2007 Supplement
Vol. 5, No. 3
 



Jun 2007 
Vol. 5, No. 6



Jul 2007 
Vol. 5, No. 7



Sep 2007 Supplement
Vol. 5, No. 5
 



Sep 2007 
Vol. 5, No. 8



Oct 2007 
Vol. 5, No. 9



Oct 2007 Supplement
Vol. 5, No. 6
 



Nov 2007 
Vol. 5, No. 10



Dec 2007 
Vol. 5, No. 11
 

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