Automated filling of drug substance is the way to go.
Human error is the main cause of operational errors and process deviations in pharmaceutical manufacturing. Automated aliquoting into single-use bags help optimize fluid management significantly. It prevents overfilling, reduces the risk of contamination, shortens operating time and prevents incompatibilities with rigid filling systems.
Among all available systems for automated filling of biopharmaceuticals and advanced therapies, RoSS.FILL, a platform for filling and filtration of primary packages, including single-use bags and bottles, outperforms its competitors in terms of a number of product features: filling accuracy, scalability, process flexibility, speed, process upgrade options and process integration.
The whitepaper provides a deep-dive into advanced fluid management of pharmaceuticals in accordance with Good Automated Manufacturing Practices (GAMP), a comparison of controlled filling solutions and the advantages of modularity for process flexibility.