Voices of Biotech
Podcast: MilliporeSigma says education vital to creating unbreakable chain for sustainability
MilliporeSigma discusses the importance of people, education, and the benefits of embracing discomfort to bolster sustainability efforts.
- Sponsored Content
- Downstream Processing
BPI Contributor
March 10, 2021
1 Min Read
Sponsored by Sartorius
Structure is an important characteristic for protein activity and function. Structural alterations due to protein mis-folding, denaturation or unfavorable conditions can lead to the formation of aggregate species that can affect the efficacy and safety of biologic drug candidates. While many biophysical analytical tools are well suited for detecting these aggregates, few offer a combination of structural and functions assessment in the same system. Sartorius’ Octet® platform is an easy-to-use analytical tool that can detect the presence of aggregated species while monitoring biologics functional activity at the formulation stage of biologics drug development process.
Octet® as a Stability Indicating Analytical Tool
Octet® Potency Assays with Aggregated Samples
Probing Structurally Altered and Aggregated States in Therapeutic Proteins
Measuring Nanoparticle Scaffold Stability
Formulations Studies on Octet® Systems
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