On May 1, 2019 at the CPhI Theater, Andy Davies, sales and marketing director at Prometic Bioseparations discussed biopharmaceutical separations, and multimode ligands. He shared that there is a trend toward using a very effective capture step — typically using affinity chromatography, where the bulk of purification is done in the initial step. More recently, scientists are beginning to adopt flow-through purification, where the target protein passes through the column, and the contaminants or impurities that still reside in the solution are captured. Multi-mode ligands use has become more common because they are extremely useful in flow-through polishing mode.
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