Voices of Biotech
Podcast: MilliporeSigma says education vital to creating unbreakable chain for sustainability
MilliporeSigma discusses the importance of people, education, and the benefits of embracing discomfort to bolster sustainability efforts.
- Sponsored Content
- Downstream Processing
BPI Contributor
November 30, 2020
20 Min View
Date: Nov 30, 2020
Duration: 20 Min
Sponsored Content
This webcast features: Romain Dabre, Senior Product Manager, Tosoh Bioscience
Downstream processing is responsible for up to 80% of the entire production costs of biotherapeutics. Given the current drive to reduce manufacturing costs for biological therapeutics, streamlining downstream processing is necessary for chromatographers and process engineers. In this presentation, we showcase the benefits of using only two chromatography processes to purify monoclonal antibodies compared to the standard industrial process. Combining high-performance Protein A capturing and a single polishing step on salt-tolerant anion-exchange resin, we could reduce the downstream costs by 45%.
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