Voices of Biotech
Podcast: MilliporeSigma says education vital to creating unbreakable chain for sustainability
MilliporeSigma discusses the importance of people, education, and the benefits of embracing discomfort to bolster sustainability efforts.
July 20, 2015
Sponsored by Natrix
Strong anion exchange (Q) chromatography is an industry standard for polishing purification steps of mAb production. It is a proven technology which removes viruses, and host cell proteins from process feed streams in flow through mode.
NatriFlo HD-Q devices adsorbers feature a hydrogel membrane which combines high dynamic binding capacity and salt tolerance to deliver best-inclass performance. This makes it possible to rapidly process large sample volumes using a small disposable device.
This article examines the ability of NatriFlo HD-Q adsorbers to clear virus and host cell proteins (HCP) from partially purified (post-Protein A) MAb solutions with high productivity (6 second residence time vs. 2-5 minutes for traditional columns).
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