A New Incompressible Protein A Resin to Improve Downstream Productivity in Single-Use Applications

ProVance Columns with GraceThis webcast features: Dr. Kiran Chodavarapu, Bioprocessing Business Development Manager at W.R. Grace.

Implementation of single-use technologies and higher antibody titers upstream have put increasing pressure on downstream processes to improve efficiencies and keep pace with upstream advancements.

There continues to be a lag in the development and adoption of single-use technologies in downstream – particularly in the area of chromatography.

To help achieve the vision of a fully disposable and flexible manufacturing platform that addresses the current bottleneck in downstream processing, a new high-capacity, incompressible Protein A resin has been developed that comes pre-packed in disposable columns. The high capacity silica and bonding chemistry maximize dynamic binding capacity while controlling non-specific protein binding.

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