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BioProcess International

Covering the whole development process for the global biotechnology industry

  • Upstream
    Processing
    Bioprocessing begins upstream, most often with culturing of animal or microbial cells in a range of vessel types (such as bags or stirred tanks) using different controlled feeding, aerating, and process strategies.
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    Beginning with harvest of material from a bioreactor, downstream processing removes or reduces contaminants to acceptable levels through several steps that typically include centrifugation, filtration, and/or chromatographic technologies.
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    Many technologies are used to characterize biological products, manufacturing processes, and raw materials. The number of options and applications is growing every day — with quality by design (QbD) giving impetus to this expansion.
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Downstream Processing

Could Membrane Fouling Be a Thing of the Past?

by BPI Contributor
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February 1, 2005

Chromatography Advisor #2

by BPI Contributor
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December 1, 2004

Chromatography Advisor #1

by BPI Contributor
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November 1, 2004

Crossflow Filters Enter the Disposables Arena

by BPI Contributor
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October 1, 2004

Revolutionizing Biotherapeutic Discovery and Production

by BPI Contributor
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October 1, 2004

Production-Scale Disposable Filtration in Biomanufacturing

by BPI Contributor
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October 1, 2004

A Disposable Option for Bovine Serum Filtration and Packaging

by BPI Contributor
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October 1, 2004

Strategies for Outsourcing Validation

by BPI Contributor
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May 1, 2004

Membrane Adsorbers

by BPI Contributor
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May 1, 2004

Financially Based Modeling of Recovery Process Alternatives

by BPI Contributor
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May 1, 2004
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Editor’s Choice

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    Demonstrating Intactness of Biopharmaceutical Products: Intact Molecular-Weight Analysis and Terminal Sequencing of Proteins

BioProcess Insider News and Analysis

Recent Tweets

  • Tweet Avatar RT @PBOAssoc: Differences Put Aside As ICH Finalizes Guide On Post Approval Changes :: Pink Sheet https://t.co/62KaQtmBV6 2 days ago
  • Tweet Avatar RT @frankvinluan: Fresh off two deals with Novartis earlier this year, @IFMThera reloads w/ $55.5M to launch a new subsidiary & incub… https://t.co/TjFPZNJnMH 2 days ago
  • Tweet Avatar RT @Dan5tanton: UK #cellandgene therapy firms are worried a shortage of skilled manufacturing staff will slow growth with some conc… https://t.co/39yI5o1nrZ 2 days ago
  • Tweet Avatar RT @Dan5tanton: CBMG hopes to leverage R&D done in #China to expedite trials in US as it establishes facilities in MD, but is it l… https://t.co/89lvL3oerf 1 week ago
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Trending

  • BioProcess Insider

    MilliporeSigma: Over 90% growth comes from mAbs, despite new modality momentum

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    Fujifilm pumps $120m into US gene therapy development and manufacturing

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    Pfizer unveils biosimilar launch plans and shares view on US market

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