Wednesday June 07, 2023
  • |Subscribe
  • |Contribute
  • |About
  • |Access Your Account
  • |Register
  • |Login
  • |Home
  • |Issue Archive
    • |Featured Reports
    • |eBooks
  • |BioProcess Insider
  • |Multimedia
    • |BPI White Papers
    • |Webinars
    • |Posters
  • |BioProcess International Events
    • |BioProcess International Conference & Exhibition
    • |Cell & Gene Therapy Manufacturing & Commercialization US
    • |Well Characterized Biologics & Biological Assays
    • |Cell & Gene Therapy Manufacturing & Commercialization Europe
  • |BioProcess International Academy
  • |Events

BioProcess International

Covering the whole development process for the global biotechnology industry

  • Upstream
    Processing
    Bioprocessing begins upstream, most often with culturing of animal or microbial cells in a range of vessel types (such as bags or stirred tanks) using different controlled feeding, aerating, and process strategies.
    • Assays
    • Biochemicals/Raw Materials
    • Bioreactors
    • Cell Culture Media
    • Expression Platforms
    • Fermentation
    • Perfusion Cell Culture
    • Upstream Contract Services
    • Upstream Single-Use Technologies
  • Downstream
    Processing
    Beginning with harvest of material from a bioreactor, downstream processing removes or reduces contaminants to acceptable levels through several steps that typically include centrifugation, filtration, and/or chromatographic technologies.
    • Filtration
    • Separation/Purification
    • Viral Clearance
    • Chromatography
    • Downstream Contract Services
    • Downstream Single-Use Technologies
  • Manufacturing
    Drug products combine active pharmaceutical ingredients with excipients in a final formulation for delivery to patients in liquid or lyophilized (freeze-dried) packaged forms — with the latter requiring reconstitution in the clinical setting.
    • Biosimilars
    • Cell/Gene Therapies
    • Continuous Bioprocessing
    • Emerging Therapeutics
    • Facility Design/Engineering
    • Fill/Finish
    • Formulation
    • Information Technology
    • MAb
    • Manufacturing Contract Services
    • Personalized Medicine
    • Process Monitoring and Controls
    • Single Use
    • Supply Chain
    • Vaccines
    • Validation
  • Analytical
    Many technologies are used to characterize biological products, manufacturing processes, and raw materials. The number of options and applications is growing every day — with quality by design (QbD) giving impetus to this expansion.
    • Culture Development
    • Cell Line Development
    • Downstream Development
    • Downstream Validation
    • Laboratory Equipment
    • PAT
    • Pre-Formulation
    • Product Characterization
    • QA/QC
    • Upstream Development
    • Upstream Validation
    • Leachables/Extractables/Particulates
  • Business
    Even as it matures, the biopharmaceutical industry is still a highly entrepreneurial one. Partnerships of many kinds — from outsourcing to licensing agreements to consultancies — help companies navigate this increasingly global business environment.
    • Careers
    • CMC Forums
    • Economics
    • Intellectual Property
    • Pre-Clinical and Clinical Trials
    • Regulatory Affairs
    • Risk Management
    • BioRegions

Upstream Processing

Producing Protein Therapeutics By Mammalian Cell Culture

by BPI Contributor
October 1, 2007

Our Readers Respond

by BPI Contributor
October 1, 2007

Many Choices in Expression

by BPI Contributor
October 1, 2007

Guide to Irradiation and Sterilization Validation of Single-Use Bioprocess Systems, Part 2

by BPI Contributor
October 1, 2007

Guide to Irradiation and Sterilization Validation of Single-Use Bioprocess Systems, Part 1

by BPI Contributor
September 1, 2007

Where Do Standards Come From?

by BPI Contributor
May 1, 2007

“Single-Use” Doesn’t Necessarily Mean “Disposable”

by BPI Contributor
May 1, 2007

An Update of the Bio-Process Systems Alliance’s Latest Activities

by BPI Contributor
May 1, 2007

Single-Use Bioreactors

by BPI Contributor
May 1, 2007

Determining Endotoxin Levels and Inhibition and Enhancement of the Endotoxin Reaction

by BPI Contributor
April 1, 2007
  • <
  • 1
  • ...
  • 34
  • 35
  • 36
  • 37
  • 38
  • 39
  • 40
  • 41
  • 42
  • 43
  • ...
  • 47
  • >

  • BioProcess Insider

    Outsourcing onsite: Charles River to set up testing lab at Wheeler Bio

  • BioProcess Insider

    Personalized pipeline driving Roche to exit Vacaville site

  • Sponsored Content

    Use of DOE Screening to Select Resins for Monoclonal Antibody Purification

  • BioProcess Insider

    What comes after mRNA? Self-amplified RNA, states industry report

  • BioProcess Insider

    Moderna lays out $322m for mRNA manufacturing plant in MA

  • Sponsored Content

    Development of an IEX Purification Process for Lentiviral Vectors


BioProcess Insider News and Analysis

Recent Tweets

  • Tweet Avatar Please join us for a #BPIAskTheExpert on "Development of IEX Purification Process for Lentiviral Vectors." Date: T… https://t.co/vgK15PE2rB 3 weeks ago
  • Tweet Avatar Please join us for a #BPIAskTheExpert on "Innovation of Novel Purification Strategies – A Case Study of a Clusterin… https://t.co/7jyYh7UsoM 3 weeks ago
  • Tweet Avatar Please join us for a #BPIAskTheExpert on "Innovation of Novel Purification Strategies – A Case Study of a Clusterin… https://t.co/zokTnEdk6F 3 weeks ago
  • Tweet Avatar Please join us for a #BPIAskTheExpert on "Innovation of Novel Purification Strategies – A Case Study of a Clusterin… https://t.co/lR7nAmnryf 3 weeks ago
Follow @bioprocessintl

Explore Topics

  • Upstream Processing
  • Downstream Processing
  • Manufacturing
  • Analytical
  • Business

Publication

  • Issue Archive
  • Featured Reports
  • eBooks
  • Subscribe
Connect
Privacy policy

BioProcessIntl.com

  • White Papers
  • Posters
  • Webinars
  • BPI Theater
  • Awards
  • Register
  • Login
  • Access Your Account

Keep up with BPI

  • Email Newsletters
  • Events
  • BioProcess Insider
  • Twitter
  • LinkedIn

About BPI

  • Who We Are
  • Editorial Advisors
  • Author Guidelines
  • Advertising/Media Kit
  • List Rental/Reprints
  • Contact Us
  • Careers
BPI
twitter linkedin
Site Map|Contact
©2023 BioProcess International All Rights reserved
  • Home
  • Issue Archive
    â–¼
    • Featured Reports
    • eBooks
  • BioProcess Insider
  • Multimedia
    â–¼
    • BPI White Papers
    • Webinars
    • Posters
  • BioProcess International Events
    â–¼
    • BioProcess International Conference & Exhibition
    • Cell & Gene Therapy Manufacturing & Commercialization US
    • Well Characterized Biologics & Biological Assays
    • Cell & Gene Therapy Manufacturing & Commercialization Europe
  • BioProcess International Academy
  • Events