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Routinely Identify Low-Level Attributes - Fast and Accurately
BPI Contributor
July 20, 2017
20 Min View
Date: Jul 20, 2017
Duration: 20 Min
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This webcast features: Sibylle Heidelberger, Technical Marketing Manager for Biologics, SCIEX.
Biotherapeutic peptide mapping LC-MS acquisition methods can make it difficult to routinely identify low-level modifications, such as deamidation and oxidation.
This webinar discusses how the use of generic SWATH® Acquisition method on the benchtop X500B QTOF System and BioPharmaView™ Software allows you to confirm the identity of low-level attributes with fast and accurate batch analysis and processing.
She also presents how the use of this unbiased data-independent SWATH® Acquisition method will effectively create a high-quality digital record of a biologic sample for consistent and sensitive detection of low abundance critical quality attributes (CQAs).
You will learn:
How to utilize a simple, generic SWATH® Acquisition method to collect high-quality MS/MS on every detectable peptide in a biologic sample preparation, for confident identification of low level attributes
How to increase the throughput of routine peptide mapping analyses without compromising data quality and sensitivity
How to obtain an unbiased and complete digital record of a biologic sample that can be interrogated or compared with data from other project sites, without the need for sample reanalysis
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