Tuesday October 26, 2021
|
Subscribe
|
Contribute
|
About
|
Access Your Account
|
Register
|
Login
|
Home
|
Current Issue
|
Issue Archive
|
Featured Reports
|
eBooks
|
BioProcess Insider
|
Multimedia
|
BPI White Papers
|
Webinars
|
Posters
|
BioProcess International Events
|
BPI Conference & Exhibition – HYBRID
|
Cell & Gene Therapy US HYBRID
|
BioProcess International Academy
|
Events
Covering the whole development process for the global biotechnology industry
Upstream
Processing
Bioprocessing begins upstream, most often with culturing of animal or microbial cells in a range of vessel types (such as bags or stirred tanks) using different controlled feeding, aerating, and process strategies.
Assays
Biochemicals/Raw Materials
Bioreactors
Cell Culture Media
Expression Platforms
Fermentation
Perfusion Cell Culture
Upstream Contract Services
Upstream Single-Use Technologies
Downstream
Processing
Beginning with harvest of material from a bioreactor, downstream processing removes or reduces contaminants to acceptable levels through several steps that typically include centrifugation, filtration, and/or chromatographic technologies.
Filtration
Separation/Purification
Viral Clearance
Chromatography
Downstream Contract Services
Downstream Single-Use Technologies
Manufacturing
Drug products combine active pharmaceutical ingredients with excipients in a final formulation for delivery to patients in liquid or lyophilized (freeze-dried) packaged forms — with the latter requiring reconstitution in the clinical setting.
Personalized Medicine
Single Use
Supply Chain
Vaccines
MAb
Biosimilars
Cell/Gene Therapies
Emerging Therapeutics
Facility Design/Engineering
Continuous Bioprocessing
Fill/Finish
Formulation
Information Technology
Manufacturing Contract Services
Process Monitoring and Controls
Analytical
Many technologies are used to characterize biological products, manufacturing processes, and raw materials. The number of options and applications is growing every day — with quality by design (QbD) giving impetus to this expansion.
Culture Development
Cell Line Development
Downstream Development
Downstream Validation
Laboratory Equipment
PAT
Pre-Formulation
Product Characterization
QA/QC
Upstream Development
Upstream Validation
Leachables/Extractables/Particulates
Business
Even as it matures, the biopharmaceutical industry is still a highly entrepreneurial one. Partnerships of many kinds — from outsourcing to licensing agreements to consultancies — help companies navigate this increasingly global business environment.
Careers
CMC Forums
Economics
Intellectual Property
Pre-Clinical and Clinical Trials
Regulatory Affairs
Risk Management
BioRegions
Read Now
Read Now
Read Now
View Now
Read Now
Download Now
Featured Content
Podcast: GSK’s digital twin approach to vaccine development
GSK relates its experience of adopting digital twin technology for vaccines on the latest episode of BioProcess Insider's podcast.
Read Now
eBook: Process-Related Impurities — Emerging Strategies for Detection, Identification, and Management of Host-Cell Proteins
Presentations at the 2021 BEBPA HCP Conference highlighted the increasing prominence of MS and platform assays for HCP detection.
Read Now
Improving Cell Manufacturing Outcomes Using In-Line Biomarker Monitoring
Dynamic Sampling Platform technology enables in-line measurement of CQA content and biomarker monitoring to optimize ATMP workflows.
Read Now
Emerging Strategies for Drug Product Comparability and Process Validation: Part 1 — Analytical Tools and Drug Product Comparability
Development of successful drug product comparability studies requires a clear sense of what attributes to test, how, and within what limits.
Read Now
How Capacitance Measurement Can Improve Viral Vector and Virus-Based Vaccine Production
Sponsored
In-line capacitance measurement can produce a detailed fingerprint of cell culture processes, facilitating scale-up of vaccine production.
Read Now
Single-Use Systems for Storing and Shipping Frozen Drug Materials
Sponsored
Thermal testing single-use systems and related aseptic connectors ensures product compatibility reduces risk in freeze-thaw processing of drug materials
Read Now
Using Prior Knowledge to Estimate Long-Term Variation
Compared with conventional approaches, using a mixed-effects model and prior knowledge improves estimates of long-term bioprocess variation.
Read Now
Stability Testing: Monitoring Biological Product Quality Over Time
Biological drug products require complex stability testing methods because they do not follow linear, first-order degradation kinetics.
Read Now
Home
Current Issue
Issue Archive
â–¼
Featured Reports
eBooks
BioProcess Insider
Multimedia
â–¼
BPI White Papers
Webinars
Posters
BioProcess International Events
â–¼
BPI Conference & Exhibition – HYBRID
Cell & Gene Therapy US HYBRID
BioProcess International Academy
Events
