Author Archives: Dan Stanton

Fill & finish investments plus pandemic drive Catalent’s biologics biz

Biologics now represent over half of Catalent’s revenues with the firm citing drug product manufacture as a major driver. For a number of years, contract development manufacturing organization (CDMO) Catalent has been tipping the balance of its business away from its small molecule and delivery technology heritage, and towards its biologics business. The biologics business pulled in around 32% of Catalent’s business mix in 2019, but in under two years the division pulled in over half of the CDMO’s net revenues…

Eppendorf $100m of capacity expansions reflects record year

Eppendorf says it will continue investing in production capabilities and infrastructure as it reports a record 12 months. German life sciences tool provider Eppendorf reported revenues of €967 million($1.16 billion) for its fiscal year 2020, up 20.3% on the year prior. “2020 was by far the most successful fiscal year for the Eppendorf Group,” co-CEOs Eva van Pelt and Peter Fruhstorfer said in a joint statement. Like many of its fellow bioprocess suppliers, growth in sales across many of Eppendorf’s…

Survey highlights lack of minority leadership in life science space

The lack of ethnic minorities and women in leadership roles is the biggest problem with diversity and inclusion in the life sciences space, according to a survey from Informa Connect. Over 480 people working across the life sciences space responded to a survey entitled ‘Diversity, Equity and Inclusion in the Life Sciences 2021,’ conducted by Informa Connect in March, and the results are now in. While respondents stressed that a combination of many problems plagued our industry, over a third…

SBI hoping to kickstart digital bioprocessing revolution through aquila buy

Scientific Bioprocessing (SBI) says it is aiming to create a digital platform to enhance biopharmaceutical workflow through the acquisition of smart sensor and data analytics firm aquila biolabs. Life sciences tool supplier Scientific Industries, through its subsidiary SBI, has acquired aquila biolabs, adding smart sensors and data analytics software for bioprocessing along with facilities in Baesweiler, Germany. “From the earliest interactions with the aquila biolabs team, it became really apparent that we shared the vision of developing technologies that can…

Avantor upping single-use capacity by 30% in response to huge demand

Avantor says investments in facilities in North Carolina, Massachusetts, and The Netherlands will help feed the surge in demand for single-use equipment driven by a robust biologics sector and the COVID-19 pandemic. Sean DeFusco, general manager of single-use solutions/fluid handling at Avantor, told BioProcess Insider the firm will increase its single-use manufacturing footprint by 30% in the United States and Europe along with doubling cleanroom space. “So far, we expanded our Morrisville, North Carolina single-use facility and we’re nearing completion…

Single-use lead times up to 12 months as COVID takes its toll

Some biomanufacturers are waiting up to a year for single-use equipment, according to ABEC. And while vendors are expanding capacity these projects will take months to come online. Early in the COVID-19 pandemic, single-use bioprocess systems and materials were highlighted as necessary tools in the development and commercial manufacture of potential vaccines and therapies. The speed and flexibility needed to make novel vaccines, including mRNA, DNA, and viral vectors, meant those platforms were largely built on single-use technologies. Coupled with…

GMP deficiencies disrupt production of ERC’s cell-based vaccine

European regulators have suspended the distribution of autologous and allogeneic cell-based vaccine candidate Gliovac following an inspection at ERC’s site in The Netherlands. The inspection took place on February 25 at the Schaijk facility, located about 75 miles southeast from Amsterdam, and resulted in a statement of non-compliance with good manufacturing practice (GMP) being issued. “ERC The Netherlands B.V. showed a lack of ability to adhere to the principles of Good Manufacturing Practice for ATMPs [advanced therapy medicinal products],” the…

Emergent recognized cross contamination risk at Bayview plant hit with 483

Emergent BioSolutions has defended the manufacture of two different viral products from its Bayview facility as part of the “Herculean task” of tackling the coronavirus pandemic. The Bayview, Maryland drug substance facility has been on the forefront of the fight against COVID-19, with Emergent BioSolutions contracted to make millions of doses of Johnson & Johnson and AstraZeneca’s respective vaccines from the plant. But an ingredient mix up reported in March rendered 15 million doses unusable, and Emergent has now halted…

Lonza’s alleged need for Nestlé staff highlights shortage in biopharma talent

Neither company will confirm reports that Nestlé staff have been commandeered to help Lonza service its Moderna contract but the story highlights biomanufacturing staffing issues. A report by Reuters this week claims contract development and manufacturing organization (CDMO) Lonza is adding staff from fellow Swiss firm Nestlé in order to service a deal to produce drug substance for hundreds of millions of doses of Moderna’s COVID-19 vaccine. The “call for volunteers” following an intervention by the Swiss government aims at…

Vendors continuing to reap the COVID windfall

Danaher expects COVID-19 vaccine and therapy-related revenue for its bioprocess businesses Pall and Cytiva to reach $2 billion, while the pandemic fuelled “an exceptionally strong start” to Sartorius’s 2021. In June last year, the evolving coronavirus pandemic was marked out as a $14 billion opportunity for bioprocess vendors by analysts. Ten months on, with several vaccines and therapies being used commercially and several more moving through the clinic, the service firms are experiencing unprecedented demand for their equipment and tools…