Author Archives: Nick Troise

PendoTECH Sensors and Industry 4.0: Integrating a PendoTECH Single-Use Sensor System with a Digital Highway

Biopharmaceutical manufacturing is evolving with the progression of Industry 4.0. Industry 4.0 refers to the ongoing “fourth industrial revolution,” which is transforming modern manufacturing and production practices through the use of “smart” technology. This is appealing especially to the biopharmaceutical industry, where production can be a long, meticulous, complex process, and optimizing manufacturing procedures is critical for success. As a leading supplier of single-use technology for the biopharmaceutical industry, PendoTECH recently has explored how its products can be integrated easily…

Validation of a Next-Generation Single-Use Turbidity System

Turbidity describes the relative clarity of a liquid as the result of suspended solids. Instruments that measure turbidity typically use a beam of light to detect particles by measuring the difference between the amount of light emitted from the light source and the amount that is received by a detector. Such measurements are affected by the size, shape, and number of particles in a sample of liquid because those solids scatter the incoming light, which provides an apparent absorbance that…

Improved Single-Use Technology for Online Turbidity Measurements

Turbidity is the relative clarity of a liquid as the result of suspended solids. Typically, turbidity measurements are taken by using a beam of light to detect the presence of particles and measuring the difference between the amount of light that is emitted from a source and the amount received by a detector. In bioprocess operations, liquid turbidity often is measured postfiltration to detect “break through,” or undesired materials coming from a filter, which provides an overall assessment of filter…