Application Note: Early-Stage Process Optimization for Seamless Scaling of MSC Therapies

Sartorius

May 13, 2022

1 Min Read
Application Note: Early-Stage Process Optimization for Seamless Scaling of MSC Therapies

A single dose of MSC therapy could consist of billions of cells per patient. To sustainably meet this clinical demand, cell expansion processes must be transformed from static cultures to suspension-based systems. This application note describes an efficient approach to process optimization in a scale-down model for suspension-based cell expansion.

Read more to learn how to:
• Comprehensively screen media and components for optimal cell growth
• Rapidly characterize phenotypic and functional CQAs of MSCs
• Develop process knowledge early in development to set the stage for seamless scale-up



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