DNA Encoded Library Platform at WuXi AppTec

On Wednesday, 5 June 2019, Letian Kuai delivered a presentation to the BPI Theater at BIO about the role of machine learning in drug design. In many cases, Kuai said, drugs are developed by accident. Researchers are beginning to leverage artificial intelligence to make those accidents occur more quickly and predictably. To that end, WuXi has developed a DNA encoded library (DEL) platform based on combinatorial chemistry principles and bolstered by artificial intelligence. This technology, Kuai suggests, could enable unprecedented chemical diversity and ease of asset development, as well as fast turnaround times for drug design and development.

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