Voices of Biotech
Podcast: MilliporeSigma says education vital to creating unbreakable chain for sustainability
MilliporeSigma discusses the importance of people, education, and the benefits of embracing discomfort to bolster sustainability efforts.
- Sponsored Content
- Downstream Processing
BPI Contributor
June 3, 2021
20 Min View
Date: Jun 3, 2021
Duration: 20 Min
Sponsored by Bio-Rad
This webcast features: Xuemei He, PhD, R&D Manager of Chromatography Media Chemistry, Bio-Rad Laboratories
New biotherapeutic constructs continue to increase in biopharmaceutical development, extending treatment options to a broad range of diseases we face today.
These biopharmaceuticals include recombinant proteins, monoclonal antibodies, antibody drug conjugates, bispecifics, viruses, and virus-like particles to mention a few. A simple, straightforward approach to the production of these biomolecules is required to meet the current demand for process efficiency and economics. Innovative chromatographic methods facilitate the achievement of desired drug purity and yield.
During this webcast, we showcase the unique selectivity of mixed-mode chromatography and detail the use of buffer additives for optimal target purity and yield.
Key Takeaways
The synergistic effects of ligand structural moieties
The modulation of ligand–biomolecule interactions with buffer pH, conductivity, and additives
The intuitive mechanism-based chromatography method development
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