Reducing Risk and Improving Timelines in the Design, Development, and Manufacture of Antibody Drug Conjugates

In his talk at the CPhI Theater on Tuesday April, 30, 2019, Juan Cordova, a principal scientist in bioconjugation at Abzena, explained how a single-use membrane absorber can improve the manufacturing of antibody drug conjugates (ADCs). An ADC process usually entails resin-based chromatographic separations that take considerable time, require tedious cleaning, and need validation of packing procedures. Substituting conventional resin-based media with single-use membrane absorbers, Cordova suggests, can expedite the timeline for ADCs’ complex manufacturing process.

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