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Podcast: MilliporeSigma says education vital to creating unbreakable chain for sustainability
MilliporeSigma discusses the importance of people, education, and the benefits of embracing discomfort to bolster sustainability efforts.
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Single-Use Stirred-Tank Bioreactors: A Commercially Viable Strategy for Cell Therapy Manufacturing
BPI Staff
July 18, 2019
1 Min Read
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Representing Hitachi Chemical Advanced Therapeutic Solutions, Alex Klarer spoke to the BPI Theater at BIO on Tuesday, 4 June 2019, about ways to improve patient access to revolutionary T-cell immunotherapies. A feasible solution, Klarer contended, is to develop a form of stirred-batch bioculture that reduces the entire manufacturing process while still maintaining high expansion rates with low media use. To establish this as a possibility, Klarer described his firm’s experiments with small and large batches on a Distek cell culture platform. Using this system, Hitachi yielded higher mass transfer rates while keeping cost of goods (CoG) in check. These findings suggest significant cost savings for drug developers and patients alike.
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