Cell culture and bioprocessing conventional wisdom remains a hurdle for the wider adoption of more precise tools. It has been more than 60 years since any real progress has been made towards creating a more accurate and reliable way of performing cell culture monitoring to better understand the effects of things like pH and oxygen at the pericellular level. At SBI, weâ€™re developing optical sensing technologies that unlock the “black box” of cell culture to bring actionable insights to scientists and researchers for faster scale-up. The flexibility of optical sensors allows for real-time monitoring anywhere within a culture vessel or bioreactor, making experiments more reproducible. In this report, weâ€™ve pulled together a list of five heresies of cell culture that have been published in peer-reviewed journal articles to illustrate the required transition from conventional cell culture wisdom to this new and better way forward for scientists and researchers.
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