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BioProcess International

Covering the whole development process for the global biotechnology industry

  • Upstream
    Processing
    Bioprocessing begins upstream, most often with culturing of animal or microbial cells in a range of vessel types (such as bags or stirred tanks) using different controlled feeding, aerating, and process strategies.
    • Assays
    • Biochemicals/Raw Materials
    • Bioreactors
    • Cell Culture Media
    • Expression Platforms
    • Fermentation
    • Perfusion Cell Culture
    • Upstream Contract Services
    • Upstream Single-Use Technologies
  • Downstream
    Processing
    Beginning with harvest of material from a bioreactor, downstream processing removes or reduces contaminants to acceptable levels through several steps that typically include centrifugation, filtration, and/or chromatographic technologies.
    • Filtration
    • Separation/Purification
    • Viral Clearance
    • Chromatography
    • Downstream Contract Services
    • Downstream Single-Use Technologies
  • Manufacturing
    Drug products combine active pharmaceutical ingredients with excipients in a final formulation for delivery to patients in liquid or lyophilized (freeze-dried) packaged forms — with the latter requiring reconstitution in the clinical setting.
    • Personalized Medicine
    • Single Use
    • Supply Chain
    • Vaccines
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    • Biosimilars
    • Cell/Gene Therapies
    • Emerging Therapeutics
    • Facility Design/Engineering
    • Continuous Bioprocessing
    • Fill/Finish
    • Formulation
    • Information Technology
    • Manufacturing Contract Services
    • Process Monitoring and Controls
  • Analytical
    Many technologies are used to characterize biological products, manufacturing processes, and raw materials. The number of options and applications is growing every day — with quality by design (QbD) giving impetus to this expansion.
    • Culture Development
    • Cell Line Development
    • Downstream Development
    • Downstream Validation
    • Laboratory Equipment
    • PAT
    • Pre-Formulation
    • Product Characterization
    • QA/QC
    • Upstream Development
    • Upstream Validation
    • Leachables/Extractables/Particulates
  • Business
    Even as it matures, the biopharmaceutical industry is still a highly entrepreneurial one. Partnerships of many kinds — from outsourcing to licensing agreements to consultancies — help companies navigate this increasingly global business environment.
    • Careers
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    • Economics
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    • Pre-Clinical and Clinical Trials
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    • BioRegions

Multimedia

White Papers

Fragment-Based Screening in Drug Discovery: How to Improve Hit Rates & Deliver Higher-Value Targets

Enabling Vaccine Production: Solving Challenges

Single-Use Systems: Globalizing Best Practices and Technology Specifications

All White Papers

Webinars

AAV Suspension Platform Generations: Continuous Improvement Leading to Increased Viral Vector Titer and Yield

Exploring New and Improved Analytical Methods for Traditional and Unique Modalities

Analytical Ultracentrifugation for Characterization of AAV Gene Delivery Vectors

All Webinars

Podcasts

Novo Nordisk Pharmatech: Brand Launch Interview

BioProcess International European Summit 2015 – Speaker Interviews

BPI Revisited: Improving IEX Throughput and Performance with Differentiated Chromatography Sorbents

All Podcasts

Posters

Evaluation Of a New Glucose Control Strategy Using CITSens Bio APC (Automated Process Control) for CHO Fed-Batch Application

High Productivity and Process Economy in GxP Applications with the Octet™ Platform

Accelerate Cell and Gene Therapy Development and Manufacturing with Fully Integrated Closed CAR-T Cell...

All Posters

BPI Theater

Manufacture of CRISPR RNPs for Clinical Use

Technology Integrators in Cell and Gene Therapy: Powering Innovation

Development of an Advanced Gene Therapy Platform

All Theater

Author Audio

December 2014 Issue Author Insights

November 2014 Issue Author Insights

October 2014 Issue Author Insights

All Author Audio

Editor’s Choice

  • BioProcess Insider

    Moderna has the capacity but cannot guarantee the supply of COVID-19 vaccine

  • BioProcess Insider

    Fujifilm $2bn US expansion plan to triple global mammalian capacity

  • Sponsored Content

    The next frontier of CAR-T cell therapies: Allogeneic workflows

  • BioProcess Insider

    Plan to make 1.3bn vaccines in 2021 places strain on Pfizer’s production network

  • BioProcess Insider

    COVID-19 has spurred long-lasting innovation, says expert

  • Sponsored Content

    Reducing Risk in Bioproduction with Facilities Equivalency

BioProcess Insider News and Analysis

Recent Tweets

  • Tweet Avatar @thermofisher adds EU viral vector plants in €725m @Novasep deal: TF Boosts #CDMO gene therpay biz, while Novasep d… https://t.co/iHylkRjibs 3 days ago
  • Tweet Avatar RT @Dan5tanton: Moderna says it has capacity to deliver 1 billion doses of its mRNA COVID-19 vaccine but with raw materials in high… https://t.co/5e5BAjWjUN 4 days ago
  • Tweet Avatar RT @Dan5tanton: CureVac has hired Bayer to help develop mRNA-based medicines including the COVID-19 vaccine candidate, CVnCoV. Baye… https://t.co/vqwFjo1Kmx 1 week ago
  • Tweet Avatar RT @Dan5tanton: Up on the downstream: Sartorius Stedim Biotech says it continues to take on the challenges in efficient downstream… https://t.co/qsAJVTPzZW 2 weeks ago
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