March 1, 2010
Laboratory Instruments
Product: Cubis laboratory balance and Arium Pro laboratory water purification system
Applications: Precision medical and life-science laboratory work
Features: International Forum Design GmbH awarded Sartorius the 2010 international iF Product Design Award for two laboratory products in the medicine/healthcare category. Cubis modular laboratory balances can be custom-configured for different working environments. The Arium Pro laboratory water purification system produces ultrapure water quickly, safely, and cost-effectively for chromatography, cell cultivation, and protein purification laboratory applications.
Contact Sartorius AG
Tangential-Flow Filtration
Product: T-series TFF cassettes
Applications: Protein purification
Features: Pall’s T-series tangential-flow filtration cassettes offer significant improvements in their materials of construction and design with proven membranes to reduce revalidation requirements. New materials are durable and stable, are low in extractables, and offer broad chemical compatibility. Designed for optimal mass transfer, scalable T-series cassettes are available with Omega PES or Delta regenerated cellulose membranes for high flux, high selectivity, and low protein binding in a variety of processes.
Contact Pall Life Sciences
Depth Filtration
Product: Nano-Ceram LR high-performance pleated filter cartridges
Applications: Intended to replace lenticular filters
Features: Each NanoCeram-LR filter cartridge contains Argonide’s patented nonwoven matrix infused with nanoalumina fibers for an electropositively charged depth filter. These remove small particles, bacteria, and viruses from water at high flow rates. Cassettes fit most lenticular housings, and results often outperform ultrafiltration for ultrapure water. Optional NanoCeram-PAC technology integrates powdered activated carbon into the media for removing halogens and most soluble organics.
Contact Argonide Corporation
Life-Science Equipment
Literature: 2010 NBS life-science equipment catalog
Applications: Performance assessment and optimization for automated liquid handlers
Features: New Brunswick Scientific’s 2010 catalog is available online and in hard copy. New products include the 5-and 14-L CelliGen BLU single-use stirred-tank bioreactor, the versatile BioFlo 610 sterilizable-in-place mobile pilot plant fermentor, and the new benchmark for SCADA software user-friendliness: NBS’s next-generation PC-based BioCommand system. The catalog also features >40 biological shakers, advanced CO2 incubators and ULT freezers, as well as several new bioprocessing systems.
Contact New Brunswick Scientific
Live Cell Analysis
Product: Cell-IQ system
Applications: Cell line development, drug discovery, stem cells
Features: Developed by Finnish company Chip-Man Technologies, the automated Cell-IQ live cell observation and analysis system is now exclusively sold by TAP in North America. A cell culture incubator, microscope, light source, and high-resolution camera are integrated with image analysis software that automatically monitors, records, and quantifies changes in cell morphology and distribution without labels or dyes. Cells can be maintained in plates under optimal growth conditions for days or weeks for consistent data quality with minimal user intervention.
Contact The Automation Partnership
Fluid-Path Assemblies
Literature: OneTouch FPA brochure
Applications: Aseptic processing
Features: Meissner Filtration Products literature features its One-Touch single-use fluid-path assemblies designed for secure fluid transfer in critical biopharmaceutical processing applications. The brochure illustrates a number of common FPA process configurations using Meissner’s library of prequalified components. Assemblies can include capsule filters for applications requiring filtration of 10-mL to >10,000-L volumes. Gamma irradiation data are covered as well. These assemblies can be customized and include dynamic combinations of connectivity, tubing, and other components.
Contact Meissner Filtration Products
Single-Use Sensors
Product: TruFluor and TruTorr sensors
Applications: Single-use bioreactors
Features: Finesse single-use GMP-qualified sensors come with Thermo Scientific HyClone’s single-use containers and bioreactors and are integrated into the Finesse turn-key bioreactor system for 25–2,000 L process volumes. TruFluor sensors optically measure pH and dissolved oxygen using real-time phase fluorimetry. The TruTorr system measures headspace pressure. These USP class VI compliant, precalibrated sensors automatically compensate for temperature.
Contact Finesse Solutions LLC
QC Automation
Products: Dip and Read residual protein A detection kit and Sidekick offline biosensor immobilization station
Applications: Quality control assays on the Octet platform
Features: The protein A detection kit includes biosensors and reagents for quantitating protein A or its biosimilars in the presence of human IgG antibodies. With the same sensitivity as other methods, this assay requires less hands-on work and can be completed in half the time. The Sidekick station provides off-line, simultaneous, and uniform sample loading on all 96 biosensors in an Octet tray. It shakes samples, keeping the biosensors immobile, to decrease required incubation time and increase the sensitivity of sandwich assays.
Contact ForteBio Inc.
Mycoplasma Detection
Product: MilliPROBE detection system
Applications: Mycoplasma detection
Features: The MilliPROBE system integrates Millipore sample preparation technologies with molecular diagnostics technologies developed by Gen-Probe, Inc. (licensed to Roka Bioscience). Mycoplasma bacteria are difficult to detect and eliminate and can have costly consequences for biopharmaceutical manufacturers. This newest assay in the MilliPROBE platform cuts mycoplasma detection time from 28–35 days to just four hours. Faster and more robust detection enables biopharmaceutical manufacturers to test more frequently and take corrective action earlier in production process, reducing financial risks and optimizing product yields.
Contact Millipore Corporation
Label-Free Analysis
Product: SPRimager II platform label-free peptide arrays
Applications: Antibody analysis
Features: Peptides make attractive affinity probes because of their robustness and specificity. This format allows users to analyze crude samples, saving the time and expense of purification. The array format increases the number of samples per test while decreasing the quantities of material needed. Label-free analysis facilitates collection of real-time interaction data and valuable affinity information. These peptide arrays allow specific detection of antibody targets in serum and egg yolks.
Contact GWC Technologies
Biobanking
Product: Nautilus software
Service: Fisher BioServices
Applications: Biological sample maintenance, analysis, and retrieval
Features: Nautilus biospecimen tracking software is designed for specimen collection, tracking, and storage with data capture, location management, chain-of-custody, and handling assurance. Fisher BioServices offers comprehensive, turn-key biobanking/biorepository services including collection kits, transportation, processing, testing, storage, and data management — all with remote access. Fisher BioServices currently manages >170,000,000 biological specimens, cell lines, tissues blood products and environmental samples.
Contact Thermo Fisher Scientific, Inc.
Valve–Connector
Product: Part #80206
Applications: Disposable fluid paths
Features: Qosina’s part #80206 is both a Y connector and a check valve featuring two 0.157-in. ID ports and a nonreturn valve on the female Luer lock sidearm. The housing is made of acrylonitrile butadiene styrene (ABS) plastic, and the compression-resistant silicone valve has a 43.5-psi cracking pressure. After fluid passes through, the valve returns to its normally closed position to prevent leaks. The company makes a wide range of disposable components — connectors, Luers, caps, clamps, adapters, stopcocks, valves, swabs, and spikes — at its ISO 9001:2000 and ISO 14001:2004 registered facility.
Contact Qosina
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