Products, Services, and Literature September 2008

Automated Welding

Product: M200 orbital welding system

Application: Welding power supply

Features: The orbital welding system M200 power supply offers ease of use, portability, and 200 amp capability, all at a weight of less than 50 lbs (23 kg). A high-resolution, 12.1-in. (307-mm) color industrial touch screen gives users a simple, intuitive pathway to enter weld programs. Users can choose from one of three forms to enter weld programs, including automatic weld schedule programming.

Contact: Swagelok Company www.swagelok.com

RNA Purification

Product: PureLink RNA Mini kit

Application: Phosphorylation detection

Features: The kit enables purification of total RNA from a number of cell and tissue types under 20 minutes. The protocol requires no phenol/chloroform extraction or ethanol precipitation and allows purification of up to 1,000 µg of total RNA. The resulting RNA is appropriate for all downstream applications including quantitative PCR (polymerase chain reaction), RNA amplification for microarray analysis, and others.

Contact: Invitrogen Corporation www.invitrogen.com

Single-Use Mixing

Product: Flexel 3D LevMix System for Palletank containers

Application: Liquid-in-liquid mixing and solid–liquid mixing operations

Features: The new single-use mixing solution uses the LevTech levitated impeller and the Sartorius Stedim Biotech Flexel 3D bag combined with a specially developed cubical mixing tank. Major improvements in bag installation and handling paired with the efficiency and speed of traditional mixing systems make this system a good choice for the biopharmaceutical industry. The system can be applied for liquid-in-liquid mixing and solid–liquid mixing operations that require moderate to high mixing intensity such as buffer and media preparation, product formulation/reformulation, hydration/dissolution of hydrophobic powders, bulk intermediate resuspension, viral inactivation, and final formulation.

Contact: Sartorius-Stedium www.sartorius-stedim.com

Water Decontamination

Product: AquaTec water preservation cell

Application: Biological research environments

Features: The preservation cell is designed for all types of laboratory water and for equipment from any manufacturer. It provides up to six months of protection from more than 600 types of bacteria, viruses, molds, and fungi for sample incubation and cell culture, preventing waterborne contamination in CO₂ incubators and water baths. It prevents microbial contamination of water safely, without the use of harsh chemicals, requiring no special disposal protocols. Selfregulation maintains the correct level of antimicrobial concentration regardless of water level. A peel-off reminder calendar indicates when replacement is recommended.

Contact: Thermo Fisher Scientific www.thermo.com/aquatec

Single-Use Sampling

Product: Bioreactor sampler

Application: Sampling bioreactors and fermentors

Features: Samples are drawn through nonreturn valves in about 15 seconds, eliminating additional risk of contamination in any type of bioreactor or fermentor including reusable glass and steel or single-use. Medical-grade materials (USP Class VI) under Class 10,000 cleanroom conditions require no cleaning or autoclaving. Capacity additional to the standard 6, 12, or 18 samples is available from individually packed modules. The unidirectional flow system ensures no sample returns to the vessel, eliminating contamination. It can be Gamma irradiated to 25-40 KGy to ensure sterility and pressure tested to assess integrity and ensure reliability.

Contact: Aseptika Ltd

www.aseptika.com

Biotechnology Business

Literature: Building Biotechnology: Business, Regulations, Patents, Law, Politics, Science (third edition)

Features: The well-known book on the business of biotechnology provides a comprehensive fundamentals-based overview of the broad variety of elements influencing the commercialization of biotechnology. Practical, real-world examples illustrate topics such as hidden pitfalls of common operational decisions, practical considerations in selecting business models and funding options, strategies to overcome developmental failures, and methods to leverage options to strengthen development plans.

Contact: Yali Friedman, thinkBiotech LLC www.thinkBiotech.com

Reference Standards

Literature: NIST Standard Reference Materials (SRMs) catalog

Application: Instrument calibration, QA assurance in industry, government, and academia

Features: The catalog lists more than 1,100 individual reference materials produced and sold by NIST, each with carefully assigned values for chemical composition and physical properties. SRMs are key mechanisms for verifying important measurements and developing new measurement methods. They provide users with tools establishing traceability of measurement results to NIST. Each comes with documentation containing assigned values with stated uncertainties, a material safety data sheet, if applicable, and details on use, stability, and NIST analytical methods.

Contact: NIST www.nist.gov/srm

Modular Fermentation

Product: BioFlo 510 19.5- and 40-L sterilizable-in-place fermentor

Application: Bacterial, yeast, and fungal cultures

Features: The modular intermediate-sized CGMP-compliant fermentor offers flexibility to add or remove components. The compact system offers control of up to 32 process loops from a touchscreen interface with multiple analog inputs and outputs provided for connection of up to 14 external devices. A powerful controller enables simultaneous trend graphing of eight process parameters, stores multiple batch recipes, and can be used with optional SCADA software. Numerous options and validation packages are offered.

Contact: New Brunswick Scientific www.nbsc.com/bih.htm

Laboratory Products

Literature: 2008–2009 Laboratory Filtration, Separation, and Detection Products Catalog

Application: Filtration and separation

Features: Pall Corporation’s life sciences’ catalog provides a guide to the company’s line of laboratory products for critical applications, including protein purification, protein and nucleic acid detection, analytical sample preparation, microbiological analysis and sterile filtration. Detailed application and selection guides, performance data, and easy-to-find information to help place orders quickly make the catalog a handy reference tool. In the United States, request part number 33526 for the printed catalog. A CD catalog (request part number 33529) is available with extra multimedia features.

Contact: Pall Corporation www.pall.com/lab

Filtration Products

Product: Regenerated cellulose (RC) syringe filters

Application: Particulate removal and sample preparation

Features: Syringe filters remove particulates from samples, prevent buildup and blockage of chromatography columns and frits, and minimize wear and tear on injection valves, ultimately reducing system down-time and component replacement. The membranes deliver clean samples with no detectable leachates and are compatible with HPLC, GC, IC, and CE analysis. The filters offer advantages over traditional nylon membranes for preparing biological samples including proteins, peptides, and other biomolecules. The batch-traceable products are HPLC-tested for extractables, meet quality standards including ISO, DIN, and ASTM, and come with a certificate of analysis.Contact: Phenomenex Inc. www.phenomenex.com