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- Downstream Processing
A Scalable Single-Use Two-Step Plasmid Purification Process
November 3, 2023
Date: Nov 3, 2023
Duration: 20 Min
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Sponsored by Cytiva Life Sciences
This webcast features: Simon Åberg, Senior Research Engineer, Cytiva.
The current global demand for biopharmaceuticals is over USD 300 billion, with an estimated growth of ≥ 12% annually. While MAb processes have become much more efficient, production of mRNA and viral vectors is still hindered by the requirement for a reliable source of high-quality plasmid DNA (pDNA), which typically requires multiple purification steps to achieve.
In this webinar, Cytiva will describe a scalable purification process that produces clinical-grade pDNA (>80% supercoiled pDNA) in just two steps.
Key Takeaways:
How to purify GMP-grade pDNA in a two-step chromatography process.
When to use membrane chromatography as a capture step.
A quick and easy way to analyze pDNA quantity and quality.
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