Use of DOE Screening to Select Resins for Monoclonal Antibody Purification

BPI Contributor

June 6, 2023

1 Min Read
Use of DOE Screening to Select Resins for Monoclonal Antibody Purification

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Screening resins for monoclonal antibody (mAb) purification is complicated both by the number of resins available and the myriad variables that must be considered to optimize a purification workflow. Using a systematic screening approach, such as design of experiments (DOE), can simplify resin selection by enabling a comprehensive evaluation of multiple input factors and their impact on desired outputs.
Read this whitepaper to learn more about:

  • The limitations of a templated approach

  • How to optimize chromatographic separations using DOE screening

  • DOE case studies that cover a range of separation challenges and tips for optimization


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