This webcast features: Samyuktha Shankar, Scientist II, Field Applications, BioProduction Group, Thermo Fisher Scientific. Digital PCR (dPCR) technology is being increasingly adopted in research, diagnostics, bioproduction, and environmental testing for absolute quantitation of nucleic acids. In this webinar, Thermo Fisher Scientific will discuss leveraging dPCR for absolute quantitation for lentiviral samples. They’ll demonstrate how this technique reduces variability, and improves accuracy and analytical sensitivity, even in high-background conditions. Key Takeaways: Leveraging LTR-based quantitation to enable correlation of total (genomic) and…

This webcast features: Patrick Nieuwenhuizen, Director, Principal Consultant, Quality Management & Compliance & Gerardo Gomez, PhD, Director, Service Line Lead, QMC, PharmaLex. Pharmaceutical manufacturing facilities, regardless of where they are, must meet GMP principles and procedures. There are, however, many other important and often poorly understood considerations with facility design. Beyond quality and compliance and country-specific expectations, facility design has a huge impact on decisions that both the sponsor and the contract manufacturing organization (CMO) must make. The issues faced…

This webcast features: Scott Estes, Head of Cell Line Development, Asimov. Traditional cell line development to support bioprocessing has typically relied on a “one-size-fits-all” vector, which can streamline development, but in most cases can lead to suboptimal expression levels, particularly for complex multi-specific molecular architectures. The commercial consequences are increased cost of goods, reduced facility flexibility, and in the worst case the inability to support commercial demand. In this webinar, Asimov presents their CHO Edge platform, which builds on the…

This webcast features: Kathleen McLaughlin, Senior Scientist, BioProcess R&D, Merck & Hironobu Shirataki, PhD, Senior Consultant, Scientific Affairs, Global Marketing, Bioprocess Division, Asahi Kasei Medical. There are two presentations during this webcast. Evaluation of the Planova™ BioEX Virus Removal Filter in Continuous Bioprocessing of a Monoclonal Antibody by Kathleen McLaughlin Standard batch monoclonal antibody biologics manufacturing processes are costly and time-consuming. A switch to intensified continuous processing enables much higher productivity, notably > 1.5 g/L/day over 25+ days of bioreactor…