eBook: Challenges of Commerical-Scale Autologous CAR-T Cell Manufacturing

The field of cell therapy is relatively young and advancing quickly. Both product and process innovations are needed for bringing new cell therapies to market. Success requires a deep understanding of cell biology to modify cells of interest and expand cultures to sufficient numbers for treatment. The authors discuss the current state of product and process development in autologous cell therapy as well as what is needed to meet the demand for these life-saving therapeutic treatments. Automation is the main focus along with other technologies used to produce the high numbers of doses required to treat large populations.

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