November 5, 2024
.png?width=1280&auto=webp&quality=95&format=jpg&disable=upscale "Bruker High-Throughput Raman Process Monitoring")
Sponsored by Bruker
Discover how High-Throughput Raman Spectroscopy, powered by Tornado’s patented High-Throughput Virtual Slit (HTVS™) Technology, can optimize downstream processing. This technique enables real-time monitoring and quantification of protein elution profiles during chromatographic separation processes, facilitating better process control. Raman spectrometers can outperform traditional methods like single-wavelength UV-Vis spectroscopy and HPLC, by offering detailed molecular and quantitative information in significantly less time.
Key Benefits
Fast and Accurate: Tornado Raman Spectrometers are the fastest on the market, with better Signal-to-Noise ratios and lower limits of detection compared to other Raman Spectrometers. This superior performance makes Tornado spectrometers uniquely capable of quickly and accurately measuring proteins of interest, providing quantitative and qualitative characterization information in real-time.
High Specificity: The Raman spectrum of a molecule is distinct and characteristic. This specificity enables targeted measurement of products or impurities. In fact, multiple chemical species of interest can be measured simultaneously with Raman Spectroscopy. When applied to downstream processing, specific target proteins can be quantified for column-switching, process control, and CQA determination.
Improved Process Control: Real-time measurements that quantify and characterize proteins of interest provides actionable information to improve and control the protein purification process. This in turn can increase efficiency, yield, and purity and therefore maximize profitability.
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