Innovation of Novel Purification Strategies – A Case Study of a Clusterin Scavenger Resin

Affinity chromatography resins employ target-specific ligands attached to a stationary phase and are commonly used to capture therapeutic entities in biologics manufacturing, reducing the number of required purification steps and increasing overall yield.

A less common but powerful use of affinity purification is the removal of problematic impurities, such as host cell proteins. Both techniques require high-specificity affinity ligands with sufficient capacity, stability, and suitability for clinical manufacturing.

In this webinar, we present the development of a novel scavenging resin for clusterin, a persistent CHO host cell protein commonly observed in monoclonal antibody manufacturing processes.

Key Takeaways:

Just fill out the form below to view the recorded webcast now.