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LC-MS Analytics in Bioprocessing: Automation-Driven Analysis of Product Quality Attributes and Nutrient Monitoring

BPI Contributor

October 14, 2024

1 Min Read
Waters LC-MS Analytics in Bioprocessing

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Discover how Waters integrates automation that enables process development labs to obtain earlier access to critical PQAs and other information regarding their process changes through media monitoring. The key features and updates of the Bioprocess Walk-Up Solutions with Portal include streamlined sample-to-result workflow, increased flexibility, and updated software. These enhanced analytics ensure the safety, efficacy, and consistency of therapeutic production by identifying the best cell lines and conditions thus enabling faster time-to-result and time-to-market.

Benefits

  • High throughput: Automated sample preparation using the Andrew+ Pipetting Robot with direct injection to the BioAccord LC-MS system orchestrated by OneLab software

  • Consistent Results: Enabling Protein A, clarification and dilution capabilities, automated plate sealing and immediate loading of plates into cooled sample manager reducing errors and operator’s time spent on running analytics

  • Connected Reporting: Reporting of glycoforms, LMWS, HMWS or other summary calculations have been enhanced and includes support for automated data connectivity to Ambr Systems.

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