This case study presents a scenario where a rapidly growing Contract Development Manufacturing Organization (CDMO) was faced with the challenge of expanding their process liquid and buffer preparation capacity to meet rising demand from a client. The sudden increase in campaign volumes resulted in additional capital and operational expenditures, threatening to exceed the site's resources and potentially delay production.

In response, Thermo Fisher Scientific conducted a Process Walk of the company's workflow to identify areas of potential improvement and waste elimination. Key observations highlighted that the limited availability and size of mixing equipment was creating bottlenecks, and inefficient sterile connection technology was resulting in wasted time and additional costs.

To address these challenges, Thermo Fisher proposed their Process Liquid Preparation Services. This solution aimed to maximize productivity and streamline the process liquid preparation steps, enabling the CDMO to meet current and future production demands without additional capital investments.

The results were significant: