September 1, 2024
Sponsored by Thermo Fisher Scientific
This case study presents a scenario where a rapidly growing Contract Development Manufacturing Organization (CDMO) was faced with the challenge of expanding their process liquid and buffer preparation capacity to meet rising demand from a client. The sudden increase in campaign volumes resulted in additional capital and operational expenditures, threatening to exceed the site's resources and potentially delay production.
In response, Thermo Fisher Scientific conducted a Process Walk of the company's workflow to identify areas of potential improvement and waste elimination. Key observations highlighted that the limited availability and size of mixing equipment was creating bottlenecks, and inefficient sterile connection technology was resulting in wasted time and additional costs.
To address these challenges, Thermo Fisher proposed their Process Liquid Preparation Services. This solution aimed to maximize productivity and streamline the process liquid preparation steps, enabling the CDMO to meet current and future production demands without additional capital investments.
The results were significant:
The CDMO managed to reduce their buffer prep load by 56%, which saved time and resources.
The company achieved annual savings in raw material costs.
They avoided capital and operational expenditures totaling $5.1 million in the first year.
This was achieved by directly sourcing process liquids and buffers for their eight highest volume buffers in 100L bioprocess containers through Thermo Fisher's Process Liquid Preparation Services.
The case study illustrates the importance of efficiency and strategic planning in managing rapid growth.
You May Also Like
