Reveal Information That Gives Insights: New Approaches to Sub-Visible Particle Characterization

This webcast features: Josefina Nilsson, Head of EM Services,  and, Gustaf Kylberg, Product Manager – MiniTEM, Vironova

Sub-visible particle characterization is essential when comparing sample quality after different purification steps or for the understanding of product stability. Analysis performed with MiniTEM provides both morphology and accurate quantitative data that can help speed up process and formulation development.

In this webinar you will learn:

The purity of two different Adenovirus samples were compared and analyzed. Automated image acquisition and particle classification was performed using MiniTEM™ -a compact, low voltage transmission electron microscope. The combination of visual proof and metric values is not achievable from indirect methods like dynamic light scattering, nor is it feasible with conventional EM due to the very long hours of manual work required. With MiniTEM, therefore, process operators can rapidly and reliably compare samples from different purification steps and gain valuable insights into the stability of different product formulations.